Serum concentrations of tumor necrosis factor-alpha in neonatal calves with presumed septicemia

Basit Öğe Kaydı
dc.contributor.authorBasoglu, A
dc.contributor.authorSen, I
dc.contributor.authorSevinc, M
dc.contributor.authorSimsek, A
dc.date.accessioned2020-03-26T16:55:28Z
dc.date.available2020-03-26T16:55:28Z
dc.date.issued2004
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study was performed to determine the concentrations of tumor necrosis factor (TNF) in the serum of neonatal calves with presumed sepsis and determine the correlation between serum concentrations of TNF and the severity and outcome of disease. Thirty-five sick calves <30 days old that suffered from enteritis, respiratory disease, or both were considered suitable for inclusion in this study by satisfying clinical and laboratory criteria suggestive of septicemia. At admission, blood samples were collected from all calves to determine the prevalence of high concentrations of TNF. The clinical course and outcome of disease then were recorded. Of the 35 calves with presumed sepsis, 10 had high serum TNF concentrations. Scleral injection, weak or absent suckling reflex, sternal or lateral recumbency, unresponsive or comatose state, and death rate of calves with high serum TNF concentration were greater than those values for calves without high serum TNF concentration. Calves with high serum TNF concentration had significantly lower mean IgG (P < .001), globulin (P < .0001), and calcium (P < .0001) concentrations; greater serum creatinine concentrations (P < .0001); and greater than or equal to2+ toxic changes in neutrophils than did calves without high serum TNF concentrations. Mean values for packed cell volume, band neutrophil count, and venous P-CO2 were significantly (P < .007) higher in the group of calves with high serum TNF concentration. Results of this study indicate that serum TNF concentration is correlated with clinical criteria of sepsis in neonatal calves. A close association was apparent between disease severity and serum TNF concentrations in this group of calves with presumed septicemia.en_US
dc.identifier.doi10.1892/0891-6640(2004)18<238:SCOTNF>2.0.CO;2en_US
dc.identifier.endpage241en_US
dc.identifier.issn0891-6640en_US
dc.identifier.issue2en_US
dc.identifier.pmid15058777en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage238en_US
dc.identifier.urihttps://dx.doi.org/10.1892/0891-6640(2004)18<238:SCOTNF>2.0.CO;2
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19199
dc.identifier.volume18en_US
dc.identifier.wosWOS:000220186900017en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAMER COLL VETERINARY INTERNAL MEDICINEen_US
dc.relation.ispartofJOURNAL OF VETERINARY INTERNAL MEDICINEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectcalfen_US
dc.subjectcytokine TNFen_US
dc.subjectneonatal diseaseen_US
dc.subjectsepsisen_US
dc.titleSerum concentrations of tumor necrosis factor-alpha in neonatal calves with presumed septicemiaen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Veterinary Internal Medicne - 2008 - Basoglu - Serum Concentrations of Tumor Necrosis Factor‐a in Neonatal Calves with (1).pdf
Boyut:
27.96 KB
Biçim:
Adobe Portable Document Format
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu