Intestinal Ischemia-Reperfusion and Plasma Enzyme Levels

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dc.contributor.authorÇağlayan, Fatma
dc.contributor.authorÇağlayan, Osman
dc.contributor.authorGünel, Engin
dc.contributor.authorElcuman, Yeşim
dc.contributor.authorÇakmak, Murat
dc.date.accessioned2020-03-26T16:45:01Z
dc.date.available2020-03-26T16:45:01Z
dc.date.issued2002
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractDetermination of blood levels of intracellular enzymes is an appropriate method to evaluate tissue and organ damage. To show systemic tissue damage resulting from intestinal ischemia-reperfusion, New Zealand rabbits underwent 60 min intestinal ischemia and 60 min reperfusion. Plasma samples were obtained before and at 55, 70, and 120 min after operation and enzyme levels were determined. Plasma aspartate aminotransferase (AST) showed a significant increase during reperfusion while lactate dehydrogenase (LDH) and creatine kinase (CK) levels were significantly increased at the end of ischemia and continued to be so through-out reperfusion. It is difficult to claim that enzymes arise from the intestine, but an increase of CK, LDH, and later of AST without any increase in alanine aminotransferase levels during ischemia suggests that their primary source is the injured intestine. Increased levels of plasma enzymes do not provide exact information about the location, but do reveal the presence of an injury.en_US
dc.identifier.citationÇağlayan, F., Çağlayan, O., Günel, E., Elcuman, Y., Çakmak, M., (2002). Intestinal Ischemia-Reperfusion and Plasma Enzyme Levels. Pediatric Surgery International, (18), 255-257. Doi: 10.1007/s003830100666
dc.identifier.doi10.1007/s003830100666en_US
dc.identifier.endpage257en_US
dc.identifier.issn0179-0358en_US
dc.identifier.pmid12021974en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage255en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s003830100666
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18156
dc.identifier.volume18en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGünel, Engin
dc.language.isoenen_US
dc.relation.ispartofPediatric Surgery Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectIntestinal ischemia-reperfusionen_US
dc.subjectPlasma enzyme levelsen_US
dc.titleIntestinal Ischemia-Reperfusion and Plasma Enzyme Levelsen_US
dc.typeArticleen_US

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