Long Term Used Testosterone May Cause Heart and Liver Damage

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dc.contributor.authorLok, Sefa
dc.contributor.authorTaşgın, Erdal
dc.contributor.authorDemir, Nagehan
dc.contributor.authorÖzdemir, Mehmet
dc.date.accessioned2020-03-26T17:49:29Z
dc.date.available2020-03-26T17:49:29Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe purpose of the research is to define the effects of testosterone on heart, liver, kidney and some chemical values in male rats during puberty In the research 16 Sprague dawley rats, 50 days old were used The rats were divided into two equal groups The first group was administrated testosterone, diluted with olive oil, 5 mg kg(-1) (SID) subcutaneously for 10 weeks 5 days each week The second group was only given olive oil At the end of the 10th week blood samples were taken Serum creatine kinase, creatine kinase-MB, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, blood urea nitrogen, creatinine, triglyceride, cholesterol, high density lipoprotein, amylase, total protein, albumin and calcium were measured with an auto-analyzer It was determined that while testosterone application in male rats led to increase on the serum CK-MB, CK and AST levels (p<0 05), it caused decreases on the total protein, albumin, calcium and creatinine (p<0 05) As a result, it can be stated that long term testosterone implication during puberty may lead to heart and liver defects at early ages.en_US
dc.identifier.citationLok, S., Özdemir, M., Taşgın, E., Demir, N., (2010). Long Term Used Testosterone May Cause Heart and Liver Damage. Journal of Animal and Veterinary Advances, 9(18), 2343-2345.
dc.identifier.endpage2345en_US
dc.identifier.issn1680-5593en_US
dc.identifier.issue18en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage2343en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25047
dc.identifier.volume9en_US
dc.identifier.wosWOS:000284033600003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorLok, Sefa
dc.institutionauthorÖzdemir, Mehmet
dc.institutionauthorTaşgın, Erdal
dc.institutionauthorDemir, Nagehan
dc.language.isoenen_US
dc.publisherMEDWELL ONLINEen_US
dc.relation.ispartofJournal of Animal and Veterinary Advancesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectTestosteroneen_US
dc.subjectCreatine Kinaseen_US
dc.subjectCreatine Kinase-MBen_US
dc.subjectAspartate Aminotransferaseen_US
dc.subjectAlbumenen_US
dc.subjectSerumen_US
dc.titleLong Term Used Testosterone May Cause Heart and Liver Damageen_US
dc.typeArticleen_US

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