Vagal nerve stimulation has robust effects on neuropsychiatric assessment in resistant epilepsy: A clinical series with clinical experiences

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dc.contributor.authorEkmekci, Hakan.
dc.contributor.authorKaptan, Hulagu.
dc.date.accessioned2020-03-26T20:19:43Z
dc.date.available2020-03-26T20:19:43Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAIM: To evaluate the resistant epileptic patients who had vagal nerve stimulation (VNS) devices implanted over five years, and to evaluate the neuropsychological aspects of VNS. MATERIAL AND METHODS: Patients with pharmacoresistant epilepsy (PRE) were followed from 2012 to 2017. Totally seven patients were found eligible for VNS in this period. In the pre-surgical period, patients were neuro-psychiatrically assessed by an independent psychiatric committee for mental status, which included assessment of intelligence quotient (IQ), Wechsler adult intelligence scale-revised (WAIS-R) IQ, Stroop test and mini-mental state examination (MMSE), Hamilton depression scale (HDS) and the Beck anxiety inventory (BAI). RESULTS: The positive effects of VNS on patients' well-being and neuropsychiatric status may be the most as important as the treatment's cost effectiveness. The patients' quality of life (QoL) was calculated just before and 12th / 24th months after VNS implantation. The pre-VNS scores for Quality of Life in Epilepsy (QoLiE-31-P) ranged from 14-59, and average score was 37.14.The post-VNS scores ranged from 31-72, and the average score was 52.86. CONCLUSION: VNS has intense effects on QoL of epileptic patients. The best approach for comparing and evaluating QoL in PRE patients may be the QoLiE-31-P inventory, which can be adapted and used in epilepsy centers to evaluate energy, mood, daily activity, cognition, medication effects, seizure worry and overall QoL.en_US
dc.identifier.citationEkmekci, H., Kaptan, H. (2019). Vagal Nerve Stimulation has Robust Effects on Neuropsychiatric Assessment in Resistant Epilepsy: A Clinical Series with Clinical Experiences. Turkish Neurosurgery, 29(2), 213-221.
dc.identifier.doi10.5137/1019-5149.JTN.23065-18.4en_US
dc.identifier.endpage221en_US
dc.identifier.issn1019-5149en_US
dc.identifier.issue2en_US
dc.identifier.pmid30649787en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage213en_US
dc.identifier.urihttps://dx.doi.org/10.5137/1019-5149.JTN.23065-18.4
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38377
dc.identifier.volume29en_US
dc.identifier.wosWOS:000460303600008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorEkmekci, Hakan.
dc.language.isoenen_US
dc.publisherTURKISH NEUROSURGICAL SOCen_US
dc.relation.ispartofTURKISH NEUROSURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectVagal nerve stimulationen_US
dc.subjectQuality of lifeen_US
dc.subjectNeuropsychiatric assessmenten_US
dc.subjectPharmacoresistant epilepsyen_US
dc.titleVagal nerve stimulation has robust effects on neuropsychiatric assessment in resistant epilepsy: A clinical series with clinical experiencesen_US
dc.typeArticleen_US

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