The Relationship Between Metabolic Syndrome and Left Ventricular Mass Index in Obese Children

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dc.contributor.authorAtabek, Mehmet Emre
dc.contributor.authorAkyüz, Esra
dc.contributor.authorEklioğlu, Beray Selver
dc.contributor.authorÇimen, Derya
dc.date.accessioned2020-03-26T18:17:11Z
dc.date.available2020-03-26T18:17:11Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: To investigate the relationships between metabolic syndrome (MS), other metabolic features and left ventricular mass index (LVMI) in a population of obese children and adolescents with MS. Methods: Two hundred and eight obese children and adolescents (119 females and 89 males, mean age: 11.9 +/- 2.7 years) and control subjects (24 females and 26 males, mean age: 11.4 +/- 2.9 years) were enrolled in the study. The insulin sensitivity index and LVMI were determined. The International Diabetes Federation criteria were used to diagnose MS. Results: The obese patients were divided into MS group (n=55) and non-MS (n=153) group. The values of LVMI in the MS group were significantly higher than those in the non-MS group (p=0.014). The present LVMI cut-off point of 33g/m(2) for the diagnosis of MS yielded a sensitivity of 97% and a specificity of 98%. LVMI was found to be positively correlated in univariate analysis with height, weight, body mass index (BMI) SDS, fasting insulin level, homeostasis model assessment of insulin resistance (HOMA-IR) and fasting glucose to insulin ratio (FGIR) and negatively correlated with quantitative insulin sensitivity check index (QUICK-I). Conclusions: We suggest that our optimal LVMI cut-off value for identifying MS may be considered as a sensitive index in screening obese children and adolescents for pediatric MS. Assessment of LVMI in obese children and adolescents may be used as a tool in predicting the presence of MS and its associated cardiovascular risks.en_US
dc.identifier.doi10.4274/jcrpe.v3i3.26en_US
dc.identifier.endpage138en_US
dc.identifier.issn1308-5727en_US
dc.identifier.issn1308-5735en_US
dc.identifier.issue3en_US
dc.identifier.pmid21911326en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage132en_US
dc.identifier.urihttps://dx.doi.org/10.4274/jcrpe.v3i3.26
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26991
dc.identifier.volume3en_US
dc.identifier.wosWOS:000497376700005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.ispartofJOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGYen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectObesityen_US
dc.subjectmetabolic syndromeen_US
dc.subjectcardiovascular diseaseen_US
dc.subjectleft ventricular mass indexen_US
dc.subjectchildrenen_US
dc.titleThe Relationship Between Metabolic Syndrome and Left Ventricular Mass Index in Obese Childrenen_US
dc.typeBook Chapteren_US

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