The Role of FDG-PET/CT in Ovarian Cancer Patients with High Tumor Markers or Suspicious Lesion on Contrast-Enhanced Ct in Evaluation of Recurrence and/or in Determination of Intraabdominal Metastases

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dc.contributor.authorSarı, O.
dc.contributor.authorKaya, B.
dc.contributor.authorÖzcan Kara, P.
dc.contributor.authorKara Gedik, G.
dc.contributor.authorÇelik, C.
dc.contributor.authorÖzbek, O.
dc.contributor.authorSerdengeçti, M.
dc.date.accessioned2020-03-26T18:31:53Z
dc.date.available2020-03-26T18:31:53Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: This retrospective study was designed to investigate the role of fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in determination of recurrence and/or intraabdominal metastasis in patients with ovarian cancer having increased tumor markers or suspicious lesion detected by a contrast-enhanced abdominal CT (ceCT). Materials and methods: A total of 34 female patients who were treated for histopathologically proven ovarian cancer, underwent PET/CT examination for restaging and suspected recurrence. Patients with pathology report, tumor marker levels, ceCT and PET/CT performed within one month were included in the study. Results: A total of 34 patients were included in the study. 25 of 34 patients had high tumor marker (CA 125) level. The remaining 9 patients had suspected recurrence on ceCT imaging with normal tumor marker levels. Recurrence was confirmed by re-operation and biopsy (n = 4), clinical and imaging follow-up (n = 21) in 25 patients with elevated tumor markers. Recurrent disease was not shown in 5 of 25 patients on ceCT imaging and 1 of 25 patients on PET/CT imaging with high CA125 values. Both ceCT and PET/CT revealed recurrent disease in 19 of 25 patients. PET/CT showed more lesions in 11 of 19 patients. Sensitivity, specificity and accuracy of the PET/CT were 96.1%, 100% and 97%, respectively. Conclusion: PET/CT is found as a beneficial method for detection of the recurrence, in patients with increased serum CA 125 level and negative CT findings or with normal CA 125 level and recurrence detected by CT which was performed due to clinical symptoms.en_US
dc.identifier.citationSarı, O., Kaya, B., Özcan Kara, P., Kara Gedik, G., Çelik, C., Özbek, O., Serdengeçti, M., (2012). The Role of FDG-PET/CT in Ovarian Cancer Patients with High Tumor Markers or Suspicious Lesion on Contrast-Enhanced Ct in Evaluation of Recurrence and/or in Determination of Intraabdominal Metastases. Revista Espanola De Medicina Nuclear, 31(1), 3-8. DOI:10.1016/j.remn.2011.03.008
dc.identifier.doi10.1016/j.remn.2011.03.008en_US
dc.identifier.endpage8en_US
dc.identifier.issn0212-6982en_US
dc.identifier.issue1en_US
dc.identifier.pmid21549452en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage3en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.remn.2011.03.008
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28561
dc.identifier.volume31en_US
dc.identifier.wosWOS:000301208600002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSarı, O.
dc.institutionauthorKaya, B.
dc.institutionauthorÖzcan Kara, P.
dc.institutionauthorKara Gedik, G.
dc.institutionauthorÇelik, C.
dc.institutionauthorÖzbek, O.
dc.institutionauthorSerdengeçti, M.
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.relation.ispartofRevista Espanola De Medicina Nuclearen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectOvarian Carcinomaen_US
dc.subjectPET/CTen_US
dc.subjectCA-125en_US
dc.subjectceCTen_US
dc.titleThe Role of FDG-PET/CT in Ovarian Cancer Patients with High Tumor Markers or Suspicious Lesion on Contrast-Enhanced Ct in Evaluation of Recurrence and/or in Determination of Intraabdominal Metastasesen_US
dc.typeArticleen_US

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