Effect of sildenafil (viagra®) on penile erection and semen volume and characteristics in kangal dogs
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Dosyalar
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada, Kangal köpeklerinde penis ereksiyonu, sperma hacmi ve özellikleri üzerine sildenafilin etkisi çalışıldı. Yaşları 3 ila 6 arasında değişen toplam 5 baş fertilitesi bilinen Kangal ırkı köpek kullanıldı. Her bir uygulamada sperma alma işleminin 60 dakika öncesinde köpeklere 50 mg dozunda oral yolla sildenafil uygulandı. Sperma toplama işlemi parmak maniplasyon yöntemiyle 3 gün arayla 12 kez denendi. Spermanın alınma işleminden sonra, sperma hacim (birinci, ikinci ve üçüncü fraksiyon yönüyle), ejakülasyon zamanı ve spermatolojik özellikler bakımından değerlendirildi. Köpekler 3 hafta dinlendirildikten sonra, sildenafil uygulaması yapılmaksızın sperma toplama işlemi parmak maniplasyon yöntemiyle 3 gün arayla 12 kez denendi. Sildenafil uygulaması, sildenafil uygulanmayan gruba göre spermanın ikinci (sırasıyla, 1.1 ve 0.7 ml) ve üçüncü fraksiyon (sırasıyla 11 ve 6 ml) hacmine önemli oranda katkıda bulundu ve total ejakülasyon zamanını artırdı (sırasıyla, 11.8 ve 7 dakika, P0.05). Fakat, sildenafil uygulanan ve uygulanmayan gruplar arasında spermatolojik özellikler yönünden önemli farklılıklar gözlenmedi (P0.05). Sonuç olarak, sidenafil penis ereksiyonu ve başarıyla spermanın toplanmasında parmak maniplasyon işleminde problem yaşayan köpeklerde kullanılabilir.
In this study, the effects of sildenafil administration on penile erection and semen volume and characteristics in Kangal dogs were studied. A total of 5 Kangal dogs, aging 3-6 years, and with a known fertility were used. In each application, sildenafil was administered orally at a dosage of 50 mg, 60 minutes prior to semen collection. Semen was collected 12 times at 3-day intervals by digital manipulation. After collected, semen was examined for volume (first, second, and third fractions), ejaculation time, and spermatological characteristics. Dogs were rested for 3 weeks after the last semen collection. Following the rest period, semen collection was experienced 12 times at 3-day intervals by digital manipulation without sildenafil application. Sildenafil administration enhanced the volume of the second and third fractions, compared to the non-sildenafil group (1.1 ml versus 0.7 ml and 11 ml versus 6 ml, respectively, P<0.05), and increased the total ejaculation time (11.8 minutes versus 7 minutes, P<0.05). On the other hand, there were no significant differences between the sildenafil and non-sildenafil groups for spermatological characteristics (P>0.05). As a conclusion, sildenafil could be used in dogs, having problems in response to digital manipulation, for penile erection and successful semen collection.
In this study, the effects of sildenafil administration on penile erection and semen volume and characteristics in Kangal dogs were studied. A total of 5 Kangal dogs, aging 3-6 years, and with a known fertility were used. In each application, sildenafil was administered orally at a dosage of 50 mg, 60 minutes prior to semen collection. Semen was collected 12 times at 3-day intervals by digital manipulation. After collected, semen was examined for volume (first, second, and third fractions), ejaculation time, and spermatological characteristics. Dogs were rested for 3 weeks after the last semen collection. Following the rest period, semen collection was experienced 12 times at 3-day intervals by digital manipulation without sildenafil application. Sildenafil administration enhanced the volume of the second and third fractions, compared to the non-sildenafil group (1.1 ml versus 0.7 ml and 11 ml versus 6 ml, respectively, P<0.05), and increased the total ejaculation time (11.8 minutes versus 7 minutes, P<0.05). On the other hand, there were no significant differences between the sildenafil and non-sildenafil groups for spermatological characteristics (P>0.05). As a conclusion, sildenafil could be used in dogs, having problems in response to digital manipulation, for penile erection and successful semen collection.
Açıklama
Anahtar Kelimeler
Veterinerlik, Köpek, Penis ereksiyonu, Sperma özellikleri
Kaynak
Kafkas Üniversitesi Veteriner Fakültesi Dergisi
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
15
Sayı
6
Künye
Çoyan, K., Ataman, M. B., Özkalp, B., Tepeli, C. (2009). Effect of Sildenafil (Viagra (R)) on Penile Erection and Semen Volume and Characteristics in Kangal Dogs. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 15(6), 855-858.
