Profiling of rutin-mediated alleviation of cadmium-induced oxidative stress in Zygophyllum fabago

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dc.contributor.authorYildiztugay, Evren
dc.contributor.authorOzfidan-Konakci, Ceyda
dc.date.accessioned2020-03-26T19:06:47Z
dc.date.available2020-03-26T19:06:47Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractZygophyllum fabago grows in arid, saline soil, or disturbed sites, such as former industrial or mining areas. This species is able to grow in coarse mineral substrates contaminated with heavy metals. To investigate the effects of the flavonoid rutin (Rtn) on certain heavy metal stress responses such as antioxidant defense systems and water status, seedlings were subjected to 100 and 200 M CdCl2 treatment without or with 0.25 and 1 mM Rtn for 7 and 14 d (days). Cd stress decreased growth (RGR), water content (RWC), leaf osmotic potential (), and chlorophyll fluorescence, all of which could be partly alleviated by addition of Rtn. Activities of superoxide dismutase, peroxidase (POX), ascorbate peroxidase, and glutathione reductase increased within the first 7 d after exposure to Cd. However, failure of antioxidant defense in the scavenging of reactive oxygen species (ROS) was evidenced by an abnormal rise in superoxide anion radical ( <mml:msubsup>O2 center dot-</mml:msubsup>) and hydrogen peroxide contents and a decline in hydroxyl radical (OH center dot) scavenging activity, resulting in enhancement of lipid peroxidation (TBARS) as a marker of Cd-induced oxidative stress. However, exogenously applied Rtn considerably improved the stress tolerance of plants via a reduction in Cd accumulation, modulation of POX activity, increase of proline (Pro) content, decrease in TBARS and ROS content and consequent lowering of oxidative damage of membrane. Overall, 0.25 and 1 mM Rtn could protect Z. fabago from the harmful effects of 100 M Cd-induced oxidative stress throughout the experiment. (c) 2014 Wiley Periodicals, Inc. Environ Toxicol 30: 816-835, 2015.en_US
dc.description.sponsorshipSelcuk University Scientific Research Projects Coordinating OfficeSelcuk University [13401084]en_US
dc.description.sponsorshipContract grant sponsor: Selcuk University Scientific Research Projects Coordinating Office.; Contract grant number: 13401084.en_US
dc.identifier.doi10.1002/tox.21960en_US
dc.identifier.endpage835en_US
dc.identifier.issn1520-4081en_US
dc.identifier.issn1522-7278en_US
dc.identifier.issue7en_US
dc.identifier.pmid24488808en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage816en_US
dc.identifier.urihttps://dx.doi.org/10.1002/tox.21960
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32469
dc.identifier.volume30en_US
dc.identifier.wosWOS:000356809300008en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofENVIRONMENTAL TOXICOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectantioxidant systemen_US
dc.subjectcadmium stressen_US
dc.subjectcadmium toxicityen_US
dc.subjectoxidative stressen_US
dc.subjectreactive oxygen speciesen_US
dc.subjectZygophyllum fabagoen_US
dc.titleProfiling of rutin-mediated alleviation of cadmium-induced oxidative stress in Zygophyllum fabagoen_US
dc.typeArticleen_US

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