Evaluation of performance of quantiferon assay and tuberculin skin test in end stage renal disease patients receiving hemodialysis

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dc.contributor.authorMaden, Emin
dc.contributor.authorBekci, T. Taha
dc.contributor.authorKesli, Recep
dc.contributor.authorAtalay, Huseyin
dc.contributor.authorTeke, Turgut
dc.contributor.authorSolak, Yalcin
dc.contributor.authorTurk, Suleyman
dc.date.accessioned2020-03-26T18:14:34Z
dc.date.available2020-03-26T18:14:34Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: End stage renal disease (ESRD) cases are associated with increased risk of tuberculosis. There is no gold standard method for detecting latent tuberculosis infection (LTBI) in ESRD. The aim of the present study was to analyze the performance of the tuberculin skin test (TST) and QuantiFERON-TB Gold in tube (QFT-G) in cases receiving hemodialysis (HD). Methods: The TST and QFT-G were prospectively performed in 96 ESRD cases undergoing HD. The agreement of the QFT-G and TST was assessed in two TST cut off values (10 mm and 5 mm) in Bacille Calmette Guerin (BCG) vaccinated and non-vaccinated cases. Results: Of 96 cases 67 were BCG vaccinated and 29 were BCG non-vaccinated. QFT-G was positive in 39.6% cases and indeterminate in 3.1%. TST was positive in 43.8% of cases in cut off value of 10 mm and positive in 58.3% of cases in cut off value of 5 mm. Agreement between TST and QFT-G results was fair in both BCG vaccinated and non-vaccinated cases in either cut off values, except in cut off value of 10 mm in BCG vaccinated cases in which the agreement was moderate. Conclusion: The agreement between QFT-G and TST test is fair and there is no significant difference in both cut off values of TST in screening of LTBI in ESRD cases receiving HD.en_US
dc.identifier.endpage356en_US
dc.identifier.issn1121-7138en_US
dc.identifier.issue4en_US
dc.identifier.pmid22143808en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage351en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26466
dc.identifier.volume34en_US
dc.identifier.wosWOS:000297603800003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEDIZIONI INT SRLen_US
dc.relation.ispartofNEW MICROBIOLOGICAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectTuberculosisen_US
dc.subjectHemodialysisen_US
dc.subjectQuantiferon testen_US
dc.titleEvaluation of performance of quantiferon assay and tuberculin skin test in end stage renal disease patients receiving hemodialysisen_US
dc.typeArticleen_US

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