Mood and anxiety disorders in patients with multiple sclerosis

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dc.contributor.authorUğuz, Faruk
dc.contributor.authorAkpınar, Zehra
dc.contributor.authorÖzkan, İshak
dc.contributor.authorTokgöz, Serhat
dc.date.accessioned2020-03-26T17:27:17Z
dc.date.available2020-03-26T17:27:17Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective. This study aims to investigate the current prevalences of mood and anxiety disorders, as well as the socio-demographic and clinical features associated with these disorders in multiple sclerosis (MS). Method. A total of 74 patients with relapsing-remitting MS (42 patients in exacerbation phase, 32 patients in remission phase) were included in the study. Mood and anxiety disorders were diagnosed by means of the Structured Clinical Interview for DSM-IV (SCID-I). The Expanded Disability Status Scale (EDSS) was used to determine degree of disability due to MS. Results. Forty-five (60.8%) patients met the criterion of at least one mood or anxiety disorder. Major depression (33.8%) was the most common psychiatric diagnosis. Generalized anxiety disorder (18.9%), specific phobia (18.9%) and obsessive-compulsive disorder (OCD) (14.9%) were other frequent psychiatric disorders. Major depression, panic disorder and OCD were significantly more common among patients in the exacerbation phase compared to patients in the remission phase. The predictors of any depressive disorder were presence of exacerbation phase of MS and higher disability level, and the predictors of any anxiety disorder were presence of exacerbation phase of MS and shorter disease duration. Conclusions. Our results suggest that the patients with relapsing-remitting MS, particularly during exacerbation phase have high prevalence of mood and anxiety disorders.en_US
dc.identifier.doi10.1080/13651500701330825en_US
dc.identifier.endpage24en_US
dc.identifier.issn1365-1501en_US
dc.identifier.issn1471-1788en_US
dc.identifier.issue1en_US
dc.identifier.pmid24916492en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage19en_US
dc.identifier.urihttps://dx.doi.org/10.1080/13651500701330825
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22522
dc.identifier.volume12en_US
dc.identifier.wosWOS:000254627000004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectmultiple sclerosisen_US
dc.subjectanxietyen_US
dc.subjectdepressionen_US
dc.subjectpsychiatric disordersen_US
dc.subjectprevalenceen_US
dc.titleMood and anxiety disorders in patients with multiple sclerosisen_US
dc.typeArticleen_US

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