Evaluation of HEMA released from four different adhesive systems by HPLC

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dc.contributor.authorAltunsoy, Mustafa
dc.contributor.authorBotsali, Murat Selim
dc.contributor.authorUlker, Hayriye Esra
dc.date.accessioned2020-03-26T19:05:57Z
dc.date.available2020-03-26T19:05:57Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: This study evaluated the elution of 2-hydroxyethyl methacrylate (HEMA) from 4 different adhesives, using high-performance liquid chromatography (HPLC). Materials and methods: The adhesives were applied on a bovine dentin surface and polymerized using an LED curing unit (n=5). After polymerization, specimens were stored in 75% ethanol solution (6 mL). Residual HEMA that was eluted from adhesives (after 10 minutes, 1 hour, 24 hours, 7 days and 30 days) was analyzed using HPLC. Statistical analyses were performed using 1-way ANOVA, Tukey HSD test and paired 2-sample t-test. Results: There were statistically significant differences among adhesive systems for the cumulative released HEMA and among the time periods (p<0.05). Clearfil SE Bond showed the highest amount of HEMA released, while Easy Bond showed the lowest. Among the time periods, the highest eluted HEMA value was detected in 10 minutes for all adhesives, and elution continued for up to 30 days. Conclusions: The HEMA eluted from adhesives was in different amounts, and the elution continued for a long time. The amount of eluted HEMA from adhesives used in this study was not viewed as critical for toxic reactions in biological tissues.en_US
dc.description.sponsorshipSelcuk University Research ProjectsSelcuk University [11202017]en_US
dc.description.sponsorshipThis study was supported by Selcuk University Research Projects (11202017).en_US
dc.identifier.doi10.5301/jabfm.5000200en_US
dc.identifier.endpageE105en_US
dc.identifier.issn2280-8000en_US
dc.identifier.issue2en_US
dc.identifier.pmid25199073en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpageE100en_US
dc.identifier.urihttps://dx.doi.org/10.5301/jabfm.5000200
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32128
dc.identifier.volume13en_US
dc.identifier.wosWOS:000362372300004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSAGE PUBLICATIONS LTDen_US
dc.relation.ispartofJOURNAL OF APPLIED BIOMATERIALS & FUNCTIONAL MATERIALSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAdhesivesen_US
dc.subjectCytotoxicityen_US
dc.subjectHPLCen_US
dc.subjectResidual HEMAen_US
dc.titleEvaluation of HEMA released from four different adhesive systems by HPLCen_US
dc.typeArticleen_US

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