The effects of osteoformin on mineralisation and quality of newly formed bone during mandibular distraction osteogenesis in rabbits

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dc.contributor.authorPampu, A. Alper
dc.contributor.authorOzkaynak, Ozkan
dc.contributor.authorSenel, Figen Cizmeci
dc.contributor.authorCankaya, Mustafa
dc.contributor.authorDolanmaz, Dogan
dc.contributor.authorErsoz, Safak
dc.contributor.authorAvunduk, Mustafa Cihat
dc.date.accessioned2020-03-26T17:40:39Z
dc.date.available2020-03-26T17:40:39Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective. The aim of this experimental study was to evaluate the effects of osteoformin on mineralization and quality of newly formed bone during distraction osteogenesis in rabbits. Study design. Distraction rate was as 1 mm/day for 5 days. In the experimental group, 100 mu g/kg osteoformin in 100 mu L/kg phosphate-buffered saline (PBS) was injected into the distraction area at day 1 and day 7 after surgery. In the control group, only 100 mu L/kg PBS was injected on the same days. On day 42, the animals were killed. Results. Bone mineral density and bone mineral content values increased significantly in the experimental group (P < .05). Newly formed bone areas, number of vessels and osteoblasts were significantly greater in experimental group (P < .05). The number of fibroblasts were also greater, but it was not significant statistically (P < .05). The number of osteoclasts was significantly lower in experimental group (P < .05). Conclusion. The results of this study show that osteoformin improves healing of regenerate in distraction osteogenesis in rabbits. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 108: 833-837)en_US
dc.identifier.doi10.1016/j.tripleo.2009.07.028en_US
dc.identifier.endpage837en_US
dc.identifier.issn1079-2104en_US
dc.identifier.issn1528-395Xen_US
dc.identifier.issue6en_US
dc.identifier.pmid19828342en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage833en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.tripleo.2009.07.028
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23938
dc.identifier.volume108en_US
dc.identifier.wosWOS:000271756800006en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMOSBY-ELSEVIERen_US
dc.relation.ispartofORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleThe effects of osteoformin on mineralisation and quality of newly formed bone during mandibular distraction osteogenesis in rabbitsen_US
dc.typeArticleen_US

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