Autoimmune thyroiditis and anti-thyroid antibodies in primary Sjogren's syndrome: a case-control study

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dc.contributor.authorTunc, R
dc.contributor.authorGonen, MS
dc.contributor.authorAcbay, O
dc.contributor.authorHamuryudan, V
dc.contributor.authorYazici, H
dc.date.accessioned2020-03-26T16:47:54Z
dc.date.available2020-03-26T16:47:54Z
dc.date.issued2004
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: To determine the frequency of antithyroid antibodies and the presence of autoimmune thyroiditis among patients with primary Sjogren's syndrome. Design: A case - control study. Methods: 53 consecutive patients with primary Sjogren's syndrome, 30 with rheumatoid arthritis, 12 with secondary Sjogren's syndrome associated with rheumatoid arthritis, 17 with autoimmune thyroiditis, and 53 apparently healthy controls were studied for anti-TG and anti-TPO antibodies as well as serum thyroid hormones and TSH levels. Results: The overall frequencies of thyroid antibodies were 6/53 (11%) in primary Sjogren's syndrome, 2/ 30 (7%) in rheumatoid arthritis, 2/12 (17%) in secondary Sjogren's syndrome, 4/53 (8%) in healthy controls, and 16/17 (94%) in autoimmune thyroiditis. There was no difference in the frequency of the thyroid antibodies among the groups if patients with autoimmune thyroiditis were excluded (p = 0.415 for anti-TPO; p = 0.275 for anti-TG; p = 0.696 for either anti-TG and/or anti-TPO). Only two patients with primary Sjogren's syndrome had clinical hypothyroidism associated with autoimmune thyroiditis. Conclusions: In this Turkish population, no association between primary Sjogren's syndrome and autoimmune thyroiditis was found.en_US
dc.identifier.doi10.1136/ard.2003.010058en_US
dc.identifier.endpage577en_US
dc.identifier.issn0003-4967en_US
dc.identifier.issn1468-2060en_US
dc.identifier.issue5en_US
dc.identifier.pmid15082490en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage575en_US
dc.identifier.urihttps://dx.doi.org/10.1136/ard.2003.010058
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18954
dc.identifier.volume63en_US
dc.identifier.wosWOS:000220813600018en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBMJ PUBLISHING GROUPen_US
dc.relation.ispartofANNALS OF THE RHEUMATIC DISEASESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleAutoimmune thyroiditis and anti-thyroid antibodies in primary Sjogren's syndrome: a case-control studyen_US
dc.typeArticleen_US

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