The effects of zinc deficiency and testosterone supplementation on leptin levels in castrated rats and their relation with LH, FSH and testosterone

dc.contributor.authorOzturk, A
dc.contributor.authorBaltaci, AK
dc.contributor.authorMogulkoc, R
dc.contributor.authorOztekin, E
dc.contributor.authorKul, A
dc.date.accessioned2020-03-26T16:58:14Z
dc.date.available2020-03-26T16:58:14Z
dc.date.issued2005
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAIM: The aim of this study was to investigate how zinc-deficiency and testosterone supplementation, both in combination and individually, affect plasma LH, FSH and leptin levels in castrated rats. DESIGN: Group 1, Control Group. Group 2, Castration Group. Group 3, Testosterone Group. Group 4, Zinc-deficient Group. Group 5, Testosterone, Zinc-deficient Group. Group 6, Zinc-deficient, Castration Group. Group 7, Testosterone, Castration Group. Group 8, Zinc-deficient, Testosterone, Castration Group. MEASUREMENTS: Plasma zinc, leptin, LH, FSH, free and total testosterone levels were measured. RESULTS: Group 2 had the highest levels of leptin and LH, besides having the highest FSH levels together with Group 6 (p < 0.01). Groups 5 and 8 had the lowest leptin levels (p < 0.01). Leptin levels in Groups 4 and 7 were higher than those in Groups 5 and 8, but lower than those in all other groups (p < 0.01). LH levels in Group 4 were not different than those in Groups 3, 5 and 8, but significantly lower than those in all other groups (p < 0.01). Free and total testosterone levels were higher in Group 4 than in castration groups that were not supplemented testosterone, but were lower in the former than in all others (p < 0.01). CONCLUSION: Plasma LH may be more effective than testosterone on plasma leptin and zinc can be an important mediator of the effect LH exercises on leptin.en_US
dc.identifier.endpage554en_US
dc.identifier.issn0172-780Xen_US
dc.identifier.issue5en_US
dc.identifier.pmid16264402en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage548en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19925
dc.identifier.volume26en_US
dc.identifier.wosWOS:000234612300020en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMAGHIRA & MAAS PUBLICATIONSen_US
dc.relation.ispartofNEUROENDOCRINOLOGY LETTERSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectcastrationen_US
dc.subjecttestosterone supplementationen_US
dc.subjectzinc deficiencyen_US
dc.subjectleptinen_US
dc.subjectLHen_US
dc.subjectFSHen_US
dc.subjecttestosteroneen_US
dc.titleThe effects of zinc deficiency and testosterone supplementation on leptin levels in castrated rats and their relation with LH, FSH and testosteroneen_US
dc.typeArticleen_US

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