The effects of zinc deficiency and testosterone supplementation on leptin levels in castrated rats and their relation with LH, FSH and testosterone
dc.contributor.author | Ozturk, A | |
dc.contributor.author | Baltaci, AK | |
dc.contributor.author | Mogulkoc, R | |
dc.contributor.author | Oztekin, E | |
dc.contributor.author | Kul, A | |
dc.date.accessioned | 2020-03-26T16:58:14Z | |
dc.date.available | 2020-03-26T16:58:14Z | |
dc.date.issued | 2005 | |
dc.department | Selçuk Üniversitesi | en_US |
dc.description.abstract | AIM: The aim of this study was to investigate how zinc-deficiency and testosterone supplementation, both in combination and individually, affect plasma LH, FSH and leptin levels in castrated rats. DESIGN: Group 1, Control Group. Group 2, Castration Group. Group 3, Testosterone Group. Group 4, Zinc-deficient Group. Group 5, Testosterone, Zinc-deficient Group. Group 6, Zinc-deficient, Castration Group. Group 7, Testosterone, Castration Group. Group 8, Zinc-deficient, Testosterone, Castration Group. MEASUREMENTS: Plasma zinc, leptin, LH, FSH, free and total testosterone levels were measured. RESULTS: Group 2 had the highest levels of leptin and LH, besides having the highest FSH levels together with Group 6 (p < 0.01). Groups 5 and 8 had the lowest leptin levels (p < 0.01). Leptin levels in Groups 4 and 7 were higher than those in Groups 5 and 8, but lower than those in all other groups (p < 0.01). LH levels in Group 4 were not different than those in Groups 3, 5 and 8, but significantly lower than those in all other groups (p < 0.01). Free and total testosterone levels were higher in Group 4 than in castration groups that were not supplemented testosterone, but were lower in the former than in all others (p < 0.01). CONCLUSION: Plasma LH may be more effective than testosterone on plasma leptin and zinc can be an important mediator of the effect LH exercises on leptin. | en_US |
dc.identifier.endpage | 554 | en_US |
dc.identifier.issn | 0172-780X | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.pmid | 16264402 | en_US |
dc.identifier.scopusquality | Q4 | en_US |
dc.identifier.startpage | 548 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/19925 | |
dc.identifier.volume | 26 | en_US |
dc.identifier.wos | WOS:000234612300020 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | MAGHIRA & MAAS PUBLICATIONS | en_US |
dc.relation.ispartof | NEUROENDOCRINOLOGY LETTERS | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.subject | castration | en_US |
dc.subject | testosterone supplementation | en_US |
dc.subject | zinc deficiency | en_US |
dc.subject | leptin | en_US |
dc.subject | LH | en_US |
dc.subject | FSH | en_US |
dc.subject | testosterone | en_US |
dc.title | The effects of zinc deficiency and testosterone supplementation on leptin levels in castrated rats and their relation with LH, FSH and testosterone | en_US |
dc.type | Article | en_US |
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