Percutaneous treatment of liver hydatid cysts: Comparison of direct injection of albendazole and hypertonic saline solution

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dc.contributor.authorPaksoy, Y
dc.contributor.authorOdev, K
dc.contributor.authorSahin, M
dc.contributor.authorArslan, A
dc.contributor.authorKoc, O
dc.date.accessioned2020-03-26T16:57:39Z
dc.date.available2020-03-26T16:57:39Z
dc.date.issued2005
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractOBJECTIVE. The purpose of this study was to compare the effect of intracystic injection of albendazole and hypertonic saline in patients with liver hydatid disease. MATERIALS AND METHODS. Fifty-nine patients with a total of 109 hydatid cysts were treated percutaneously. In all cases, local anesthesia was applied. Twenty percent hypertonic saline was used in 31 patients (40 cysts, group 1) as the scolicidal agent, and albendazole solution was used in 28 patients (69 cysts, group 2). The PAIR (percutaneous puncture, aspiration, injection, reaspiration) method was applied in group 1. In group 2, we used a different procedure that could be called the PAI (percutaneous aspiration and injection) method. After this procedure, routine sonography and CT examinations were conducted. The results of both groups were compared. RESULTS. Follow-up examinations showed that liver hydatids expanded approximately to their original size after a significant reduction during the first month. In the follow-up period, fluid contents totally disappeared; thickening and irregularities were also observed in the cyst walls and a solid, hyperechogenic, heterogeneous pseudotumor appearance representing a degenerated membrane was seen in all patients. Hypertonic saline solution inactivated the scolices from the beginning of the treatment. However, scolices were inactive in the cysts aspirated 1 month after the procedure in group 2. A significant correlation was noted between elapsed time after the treatment and the cyst size using Wilcoxon's signed rank test (P = 0.000). No difference was seen between two groups in the amount of cyst size reduction using the Mann-Whitney test (p = 0.521). CONCLUSION. In addition to its oral use, albendazole may be injected intracystically as we did in our study. It sterilizes the cyst cavity and affects scolices as well.en_US
dc.identifier.doi10.2214/ajr.185.3.01850727en_US
dc.identifier.endpage734en_US
dc.identifier.issn0361-803Xen_US
dc.identifier.issue3en_US
dc.identifier.pmid16120926en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage727en_US
dc.identifier.urihttps://dx.doi.org/10.2214/ajr.185.3.01850727
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19825
dc.identifier.volume185en_US
dc.identifier.wosWOS:000231650700026en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAMER ROENTGEN RAY SOCen_US
dc.relation.ispartofAMERICAN JOURNAL OF ROENTGENOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titlePercutaneous treatment of liver hydatid cysts: Comparison of direct injection of albendazole and hypertonic saline solutionen_US
dc.typeArticleen_US

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