Intraoperative determination of intestinal viability: A comparison with transserosal pulse oximetry and histopathological examination

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dc.contributor.authorErikoglu, M
dc.contributor.authorKaynak, A
dc.contributor.authorBeyath, EA
dc.contributor.authorToy, H
dc.date.accessioned2020-03-26T16:57:23Z
dc.date.available2020-03-26T16:57:23Z
dc.date.issued2005
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground. In this study, we aimed to measure the O-2 saturation of ischemic intestinal segments and the relationship between these measures and concomitant pathological gradings. Materials and methods. We used 14 New Zealand White rabbits, anesthetized with a combination of 80 mg/kg (i.m.) Ketamine hydrochloride and 10 mg/kg Acepromazine (i.m.). The superior mesenteric artery (SMA) was explored, and O-2 saturation was measured by pulse oximetry 5 cm proximal to the ileocecal valve at the 0th hour. At the same time a 0.5-cm. full-thickness wedge biopsy was taken from the same region. Thereafter, the SMA was ligated and the abdomen was closed. All rabbits were undertaken relaparotomy at the 4th hour; O-2 saturation was measured by pulse oximetry at 5 cm away from the region of the first biopsy and a 0.5-cm. full-thickness wedge biopsy was taken. The abdomen was then closed. The same procedure was performed at the 8th and the 12th hour. Mucosal hemorrhage, transmural congestion, mucosal necrosis, and transmural necrosis were examined in the specimens. Results. Pathologically, transmural necrosis was concomitant with 64% O-2 saturation (sensitivity: 100%; specificity: 86%). Mucosal necrosis was concomitant with 76% O-2 saturation values (sensitivity: 100%; specificity: 75%). Transmural congestion was concomitant with 81% O-2 saturation values (sensitivity: 89%; specificity: 58%). Mucosal hemorrhage was concomitant with 91% O-2 saturation (sensitivity: 100%; specificity: 31%). Conclusion. O-2 saturation measures > 76% may indicate reversible changes as mucosal necrosis, transmural congestion, or mucosal hemorrhage, and O-2 saturation measures < 64% may indicate permanent transmural necrosis. As a result, intraoperative evaluation of intestinal viability by pulse oximetry may give us an idea about the degree of pathological changes and subsequently might reduce the number of second-look operations. (c) 2005 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.jss.2005.02.007en_US
dc.identifier.endpage69en_US
dc.identifier.issn0022-4804en_US
dc.identifier.issue1en_US
dc.identifier.pmid16115494en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage66en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.jss.2005.02.007
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19774
dc.identifier.volume128en_US
dc.identifier.wosWOS:000231520200012en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherACADEMIC PRESS INC ELSEVIER SCIENCEen_US
dc.relation.ispartofJOURNAL OF SURGICAL RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectintestinal ischemiaen_US
dc.subjectpulse oximetryen_US
dc.subjectoxygen saturationen_US
dc.subjectintestinal viabilityen_US
dc.subjecthistopathological examinationen_US
dc.titleIntraoperative determination of intestinal viability: A comparison with transserosal pulse oximetry and histopathological examinationen_US
dc.typeArticleen_US

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