Is the Use of Topical Fluorescein Helpful for Management of CSF Leakage?

Basit Öğe Kaydı
dc.contributor.authorÖztürk, Kayhan
dc.contributor.authorKarabağlı, Hakan
dc.contributor.authorBulut, Serap
dc.contributor.authorEğilmez, Meryem
dc.contributor.authorDuran, Mutlu
dc.date.accessioned2020-03-26T18:30:46Z
dc.date.available2020-03-26T18:30:46Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives/Hypothesis: We aimed to evaluate the effectiveness of topical intranasal fluorescence application together with high-resolution computed tomography and magnetic resonance imaging and/or magnetic resonance cisternography for the preoperative diagnosis of cerebrospinal fluid (CSF) leakage and for intraoperative localization of CSF fistulas. We also assessed postoperative recurrence. Study Design: Descriptive study. Methods: Twenty-four cases underwent endonasal endoscopic repair for CSF leakage. Following intranasal topical application of fluorescein 10% to the middle turbinate-cribriform plate region and anterior wall of the sphenoid sinus, a color change of the fluorescein from yellow-brown to green was accepted as evidence of CSF leakage. A nasoseptal flap, collagen matrix, or fascia lata and septal cartilage graft were used for reconstruction of the CSF fistula. Results: The use of topical fluorescein application was helpful in diagnosing CSF rhinorrhea preoperatively and locating the CSF fistula intraoperatively. One case had both ethmoid roof and sphenoid sinus defects, and this case underwent a second operation for closure of the sphenoid defect. All CSF leakages were successfully repaired by endoscopic endonasal surgery using a nasoseptal flap. Conclusions: Cases with traumatic CSF leakage pose a higher risk of meningitis than the cases with spontaneous CSF leakage. Topical application of fluorescein is highly specific and sensitive in identifying preoperative, intraoperative, and postoperative CSF leakage. It is a simple, quick, and sensitive technique. The surgeon should be vigilant for multiple defects.en_US
dc.identifier.citationDuran, M., Eğilmez, M., Bulut, S., Karabağlı, H., Öztürk, K., (2012). Is the Use of Topical Fluorescein Helpful for Management of CSF Leakage?. Laryngoscope, (122), 1215-1218. Doi: 10.1002/lary.23277
dc.identifier.doi10.1002/lary.23277en_US
dc.identifier.endpage1218en_US
dc.identifier.issn0023-852Xen_US
dc.identifier.issn1531-4995en_US
dc.identifier.pmid22460742en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1215en_US
dc.identifier.urihttps://dx.doi.org/10.1002/lary.23277
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28170
dc.identifier.volume122en_US
dc.identifier.wosWOS:000304711000007en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKarabağlı, Hakan
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofLaryngoscopeen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCerebrospinal fluid leaken_US
dc.subjectcisternographyen_US
dc.subjectfluoresceinen_US
dc.subjectnasoseptal flapen_US
dc.subjectrhinorrheaen_US
dc.titleIs the Use of Topical Fluorescein Helpful for Management of CSF Leakage?en_US
dc.typeArticleen_US

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