Systemic onset juvenile rheumatoid arthritis presenting with absence of B lymphocytes
Küçük Resim Yok
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SPRINGER
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Juvenile rheumatoid arthritis (JRA) is a complex disease involving the interactions of several cell populations with different mediators. Herein, we report a five-year-old girl with systemic-onset JRA. At admission, peripheral blood flowcytometric analysis showed the percentages of CD19(+)and CD20(+) stop B cells were < 1%. These values returned to normal on the tenth day of steroid treatment. This is the first report of JRA presented with absence of B lymphocytes in the literature and suggested that lymphocytes subset analysis could change with treatment in patients with JRA. Different clinical signs and symptoms reflecting aspects of JRA are critical for the etiology of the disease and to identify new strategies for treatment.
Açıklama
Anahtar Kelimeler
juvenile rheumatoid arthritis, B lymphocyte, immune system
Kaynak
RHEUMATOLOGY INTERNATIONAL
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
27
Sayı
10
