Systemic onset juvenile rheumatoid arthritis presenting with absence of B lymphocytes

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dc.contributor.authorArtaç, Hasibe
dc.contributor.authorAlp, Hayrullah
dc.contributor.authorKeleş, Sevgi
dc.contributor.authorReisli, İsmail
dc.contributor.authorTunç, Recep
dc.date.accessioned2020-03-26T17:18:21Z
dc.date.available2020-03-26T17:18:21Z
dc.date.issued2007
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractJuvenile rheumatoid arthritis (JRA) is a complex disease involving the interactions of several cell populations with different mediators. Herein, we report a five-year-old girl with systemic-onset JRA. At admission, peripheral blood flowcytometric analysis showed the percentages of CD19(+)and CD20(+) stop B cells were < 1%. These values returned to normal on the tenth day of steroid treatment. This is the first report of JRA presented with absence of B lymphocytes in the literature and suggested that lymphocytes subset analysis could change with treatment in patients with JRA. Different clinical signs and symptoms reflecting aspects of JRA are critical for the etiology of the disease and to identify new strategies for treatment.en_US
dc.identifier.doi10.1007/s00296-007-0316-7en_US
dc.identifier.endpage983en_US
dc.identifier.issn0172-8172en_US
dc.identifier.issue10en_US
dc.identifier.pmid17252261en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage981en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s00296-007-0316-7
dc.identifier.urihttps://hdl.handle.net/20.500.12395/21644
dc.identifier.volume27en_US
dc.identifier.wosWOS:000248136700013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofRHEUMATOLOGY INTERNATIONALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectjuvenile rheumatoid arthritisen_US
dc.subjectB lymphocyteen_US
dc.subjectimmune systemen_US
dc.titleSystemic onset juvenile rheumatoid arthritis presenting with absence of B lymphocytesen_US
dc.typeArticleen_US

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