Warming and Response to Contractile Agents in Calf Cardiac Vein: Role of the Nitric Oxide

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dc.contributor.authorAtalik, Kısmet Esra
dc.contributor.authorSahin, AS
dc.contributor.authorUlusoy, HB
dc.contributor.authorDogan, N
dc.date.accessioned2020-03-26T16:46:20Z
dc.date.available2020-03-26T16:46:20Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe effects of warming on the response to various contractile agents of calf cardiac vein were studied using 2.5-mm long cylindrical segments. Concentration-response curves for carbachol (10(-9)-3 x 10(-4) M), 5-hydroxytryptamine (5-HT; 10(-8)-3 x 10(-3)), potassium chloride (KCl; 10(-4)-5 x 10(-2) m) and calcium chloride (CaCl2; 10(-4)-10(-2)) were isometrically recorded at 37 and 41degreesC (warming). During warming the sensitivity, but not the maximal response, of carbachol 5-HT, KCl, and CaCl2 was significantly higher than at 37degreesC. Warming to 41degreesC after treatment with N-G-nitro-L arginine methyl esther (10(-5) m) did not modify the effect of warming. These results suggest that nitric oxide seems to have no role in the warming-induced responses in calf cardiac vein.en_US
dc.identifier.citationAtalik, K. E., Sahin, A. S., Ulusoy, H. B., Dogan, N., (2003). Warming and Response to Contractile Agents in Calf Cardiac Vein: Role of the Nitric Oxide. Fundamental & Clinical Pharmacology, 77(1), 77-82. DOİ: 10.1046/j.1472-8206.2003.00142.x
dc.identifier.doi10.1046/j.1472-8206.2003.00142.xen_US
dc.identifier.endpage82en_US
dc.identifier.issn0767-3981en_US
dc.identifier.issue1en_US
dc.identifier.pmid12588633en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage77en_US
dc.identifier.urihttps://dx.doi.org/10.1046/j.1472-8206.2003.00142.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18626
dc.identifier.volume17en_US
dc.identifier.wosWOS:000181275000009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAtalik, Kısmet Esra
dc.institutionauthorSahin, AS
dc.institutionauthorUlusoy, HB
dc.institutionauthorDogan, N
dc.language.isoenen_US
dc.publisherBLACKWELL PUBLISHING LTDen_US
dc.relation.ispartofFundamental & Clinical Pharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCardiac veinen_US
dc.subjectContractionsen_US
dc.subjectNitric Oxideen_US
dc.subjectWarmingen_US
dc.titleWarming and Response to Contractile Agents in Calf Cardiac Vein: Role of the Nitric Oxideen_US
dc.typeArticleen_US

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