Cardiac Functions Evaluated with Tissue Doppler Imaging in Childhood Cancers Treated with Anthracyclines

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dc.contributor.authorBaysal, Tamer
dc.contributor.authorKöksal, Yavuz
dc.contributor.authorOran, Bülent
dc.contributor.authorŞen, Metin
dc.contributor.authorÜnal, Ekrem
dc.contributor.authorÇimen, Derya
dc.date.accessioned2020-03-26T17:47:20Z
dc.date.available2020-03-26T17:47:20Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim: The aim of this study was to assess the cardiac functions using conventional echocardiography and tissue Doppler imaging in childhood cancers treated with anthracyclines. Methods: The study group was selected from the patients admitted to the pediatric oncology department for a treatment protocol that included doxorubicin. Body surface area was calculated and complete 2-dimensional, M-mode, pulse wave Doppler and pulse wave tissue Doppler echocardiographic examinations were performed just before the first treatment and at least 6 months after the last treatment. Results: This study included 20 patients (12 males and 8 females). Mean cumulative antracycline dose was 189 +/- 102.90 mg/m<SU2</SU. There were no significant differences between the pre- and post-treatment groups regarding systolic and diastolic blood pressures, heart rates, left ventricular ejection fraction and fractional shortening, right and left ventricular conventional and tissue Doppler diastolic parameters (E and A waves, E/A ratio, E' and A' waves, E'/A' ratio), but there were significant differences between the pre- and post-treatment groups regarding body surface area, right and left ventricular myocardial performance index observed by conventional pulse wave and pulse wave tissue Doppler methods. Conclusion: Tissue Doppler imaging provided additional information on cardiac functions. While systolic and diastolic functions were in normal range, myocardial performance index observed by tissue Doopler method was impaired in children who were treated with anthracyclines.en_US
dc.identifier.citationBaysal, T., Köksal, Y., Oran, B., Şen, M., Ünal, E., Çimen, D., (2010). Cardiac Functions Evaluated with Tissue Doppler Imaging in Childhood Cancers Treated with Anthracyclines. Pediatric Hematology and Oncology, (27), 13-23. Doi: 10.3109/08880010903352299
dc.identifier.doi10.3109/08880010903352299en_US
dc.identifier.endpage23en_US
dc.identifier.issn0888-0018en_US
dc.identifier.pmid20121551en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage13en_US
dc.identifier.urihttps://dx.doi.org/10.3109/08880010903352299
dc.identifier.urihttps://hdl.handle.net/20.500.12395/24677
dc.identifier.volume27en_US
dc.identifier.wosWOS:000275534300002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBaysal, Tamer
dc.institutionauthorKöksal, Yavuz
dc.institutionauthorOran, Bülent
dc.institutionauthorŞen, Metin
dc.institutionauthorÜnal, Ekrem
dc.institutionauthorÇimen, Derya
dc.language.isoenen_US
dc.publisherInforma Healthcareen_US
dc.relation.ispartofPediatric Hematology and Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAnthracyclines
dc.subjectChildhood cancers
dc.subjectTissue Doppler imaging
dc.titleCardiac Functions Evaluated with Tissue Doppler Imaging in Childhood Cancers Treated with Anthracyclinesen_US
dc.typeArticleen_US

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