Expression profile and polymorphisms of actin genes in protoscoleces of Echinococcus granulosus from sheep in central Turkey
Küçük Resim Yok
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ELSEVIER SCIENCE BV
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The expression levels and polymorphisms of two actin genes, EgactI and EgactII, were investigated in the protoscoleces of Echinococcus granulosus isolated from sheep in the central region of Turkey. Only the EgactII gene was found to be expressed at detectable levels by protoscoleces in the present study. PCR-RFLP analysis and following sequence analysis revealed that a partial EgactI gene is more polymorphic than a partial EgactII gene. And, three alleles for EgactI gene were identified. In all samples, including three alleles, there were nucleotide substitutions at six positions of the partial EgactI gene, and were distinct from the reference sequence from GenBank (TM) database. These differences are referred to as the Anatolian haplotype. (C) 2009 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Echinococcus granulosus, Actin genes, Polymorphisms, Anatolian haplotype
Kaynak
VETERINARY PARASITOLOGY
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
166
Sayı
01.02.2020
