Expression profile and polymorphisms of actin genes in protoscoleces of Echinococcus granulosus from sheep in central Turkey

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dc.contributor.authorArikoglu, Hilal
dc.contributor.authorArslan, Ahmet
dc.contributor.authorHepdogru, Melda A.
dc.contributor.authorTurhan, Ahmet B.
dc.date.accessioned2020-03-26T17:38:40Z
dc.date.available2020-03-26T17:38:40Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe expression levels and polymorphisms of two actin genes, EgactI and EgactII, were investigated in the protoscoleces of Echinococcus granulosus isolated from sheep in the central region of Turkey. Only the EgactII gene was found to be expressed at detectable levels by protoscoleces in the present study. PCR-RFLP analysis and following sequence analysis revealed that a partial EgactI gene is more polymorphic than a partial EgactII gene. And, three alleles for EgactI gene were identified. In all samples, including three alleles, there were nucleotide substitutions at six positions of the partial EgactI gene, and were distinct from the reference sequence from GenBank (TM) database. These differences are referred to as the Anatolian haplotype. (C) 2009 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipUniversity Research Fund [2001/03]en_US
dc.description.sponsorshipThis research was performed at the Experimental Medicine Research and Application Center, Selcuk University and was supported by the University Research Fund (2001/03). This manuscript is the partial fulfilment of the PhD dissertation of Dr. Hilal Arikoglu. We would like to thank to the veterinarians of slaughterhouses for their assistance in the collection of Echinococcus isolates. We also thank to Ms. Ardith Jane Burnett, Fethiye, Turkey for English editing of this manuscript.en_US
dc.identifier.doi10.1016/j.vetpar.2009.08.007en_US
dc.identifier.endpage85en_US
dc.identifier.issn0304-4017en_US
dc.identifier.issn1873-2550en_US
dc.identifier.issue01.02.2020en_US
dc.identifier.pmid19716236en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage80en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.vetpar.2009.08.007
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23542
dc.identifier.volume166en_US
dc.identifier.wosWOS:000272090400013en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofVETERINARY PARASITOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectEchinococcus granulosusen_US
dc.subjectActin genesen_US
dc.subjectPolymorphismsen_US
dc.subjectAnatolian haplotypeen_US
dc.titleExpression profile and polymorphisms of actin genes in protoscoleces of Echinococcus granulosus from sheep in central Turkeyen_US
dc.typeArticleen_US

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