Echocardiographic assessment of left ventricular systolic function in neonatal calves with naturally occurring sepsis or septic shock due to diarrhea
dc.contributor.author | Naseri, Amir. | |
dc.contributor.author | Sen, Ismail. | |
dc.contributor.author | Turgut, Kursad. | |
dc.contributor.author | Guzelbektes, Hasan. | |
dc.contributor.author | Constable, Peter D. | |
dc.date.accessioned | 2020-03-26T20:13:32Z | |
dc.date.available | 2020-03-26T20:13:32Z | |
dc.date.issued | 2019 | |
dc.department | Selçuk Üniversitesi, Veteriner Fakültesi, Klinik Bilimler Bölümü | en_US |
dc.description.abstract | Sepsis is associated with clinically relevant cardiovascular changes. The objectives of this study were to evaluate the clinical value of echocardiography for monitoring left ventricular (LV) systolic function in septic calves. A prospective longitudinal study was performed using a convenience sample. Twenty septic calves and 10 healthy calves were enrolled in the study. Arterial blood pressure (BP) was measured and M-mode echocardiography performed to characterize LV systolic function; the latter included measurement of ejection fraction, EF; stroke volume, SVI and cardiac output indexed to body weight, CI; E-point of septal separation, EPSS; pre-ejection period, PEP; ejection time, LVET; ratio of PEP to LVET; velocity of circumferential shortening, Vcf, LV enddiastolic volume index (LVEDVI) and LV end-systolic volume index (LVESVI) on admission and 6, 24, 48 and 72 h later in septic calves and once in healthy calves. Admission data were compared using the Mann-Whitney U test and P < .05 was considered significant. Decreased preload and afterload were present in septic calves, as indicated by marked decreases in BP, LVEDVI, LVESVI, SVI, CI, EPSS when compared to healthy calves. Systolic function appeared adequate in septic calves, based on EF and FS compared to control calves. There was no difference in heart rate, LVET, PEP:LVET, or Vcf between septic and health calves. We conclude that circulatory dysfunction, rather than systolic dysfunction predominates in septic calves. Positive associations on admission between CI and LVEDVI, LVESVI, and SVI support this conclusion. Echocardiographic determination of LVEDVI and CI appears useful in directing treatment in septic calves. | en_US |
dc.description.sponsorship | Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [1130218] | en_US |
dc.description.sponsorship | The manuscript has been produced from thesis of Dr. Amir Naseri. This study was supported by the Scientific and Technological Research Council of Turkey (Project number 1130218). Presented, in part in abstract form, at the XXIX World Buiatrics Congress, Dublin, Ireland in 2016. | en_US |
dc.identifier.citation | Naseri, A., Sen, I., Turgut, K., Guzelbektes, H., Constable, P. D. (2019). Echocardiographic Assessment of Left Ventricular Systolic Function in Neonatal Calves with Naturally Occurring Sepsis or Septic Shock Due to Diarrhea. Research in Veterinary Science, 126, 103-112. | |
dc.identifier.doi | 10.1016/j.rvsc.2019.08.009 | en_US |
dc.identifier.endpage | 112 | en_US |
dc.identifier.issn | 0034-5288 | en_US |
dc.identifier.issn | 1532-2661 | en_US |
dc.identifier.pmid | 31445396 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | 103 | en_US |
dc.identifier.uri | https://dx.doi.org/10.1016/j.rvsc.2019.08.009 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/37714 | |
dc.identifier.volume | 126 | en_US |
dc.identifier.wos | WOS:000497251000017 | en_US |
dc.identifier.wosquality | Q1 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.institutionauthor | Naseri, Amir. | |
dc.institutionauthor | Sen, Ismail. | |
dc.institutionauthor | Turgut, Kursad. | |
dc.institutionauthor | Guzelbektes, Hasan. | |
dc.language.iso | en | en_US |
dc.publisher | ELSEVIER SCI LTD | en_US |
dc.relation.ispartof | RESEARCH IN VETERINARY SCIENCE | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.subject | Contractility | en_US |
dc.subject | Ejection fraction | en_US |
dc.subject | Systemic inflammatory response syndrome | en_US |
dc.subject | Hypotension | en_US |
dc.title | Echocardiographic assessment of left ventricular systolic function in neonatal calves with naturally occurring sepsis or septic shock due to diarrhea | en_US |
dc.type | Article | en_US |
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