Identification of Variant Translocations in Chronic Myeloid Leukemia by Fluorescence In Situ Hybridization

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dc.contributor.authorAcar, Hasan
dc.contributor.authorStewart, Janet
dc.contributor.authorBoyd, Elizabeth
dc.contributor.authorConnor, Michael J.
dc.date.accessioned2020-03-26T16:25:24Z
dc.date.available2020-03-26T16:25:24Z
dc.date.issued1997
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractWe studied two cases of chronic myeloid leukemia (CML) having variant complex translocations detected by trypsin G-banding and fluorescence in situ hybridization (FISH). Application of dual color- (DC-) FISH using abl and bcr cosmid probes permitted us to detect the bcr-abl fusion event on both interphase nuclei and metaphase spread. Furthermore, FISH using combinatorial hybridization (centromeric-library and library-library probes) demonstrated the content and the position of the translocations in CML patients with variant (complex type) Ph-positive rearrangements. FISH analysis appears to be superior than conventional cytogenetic analysis.en_US
dc.identifier.citationAcar, H., Stewart, J., Boyd, E., Connor, M. J., (1997), Identification of Variant Translocations in Chronic Myeloid Leukemia by Fluorescence In Situ Hybridization. Cancer Genetics and Cytogenetics, 93(2), 115-118.
dc.identifier.doi10.1016/S0165-4608(96)00168-9en_US
dc.identifier.endpage118en_US
dc.identifier.issn0165-4608en_US
dc.identifier.issue2en_US
dc.identifier.pmid9078295en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage115en_US
dc.identifier.urihttps://dx.doi.org/10.1016/S0165-4608(96)00168-9
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16585
dc.identifier.volume93en_US
dc.identifier.wosWOS:A1997WN73900002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAcar, Hasan
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.relation.ispartofCancer Genetics and Cytogeneticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleIdentification of Variant Translocations in Chronic Myeloid Leukemia by Fluorescence In Situ Hybridizationen_US
dc.typeArticleen_US

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