Prevalence of Behcet's Disease in Istanbul, Turkey
Yükleniyor...
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-Blackwell
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background The prevalence of Behcet's disease (BID) is much higher in countries along the ancient Silk Route, extending from Japan to Mediterranean countries including Turkey, than in northern Europe and the USA. Three previous epidemiologic surveys have been carried out in different regions of Turkey. Patients and methods This study investigated the cross-sectional prevalence of BID in individuals aged > 12 years in Istanbul, Turkey, in two stages. The first stage aimed to identify individuals with recurrent oral ulcers (ROUs) by visiting them in their homes, and the second stage aimed to further examine those with ROUs for the presence of other BID-related manifestations under hospital conditions. The sample size was determined to be 24,000 with an expected BID prevalence rate of 1/1000 and a sampling error of 4/10,000, with a 95% confidence interval (CI) of 6-14/10,000. The number of individuals to be screened in each district was determined in proportion to the population of all districts in Istanbul. Results The standard questionnaire was applied to a total of 23,986 individuals at their homes. A history of ROU was recorded in 2289 individuals (9.5%), and a previous diagnosis of BID was recorded in 47. The diagnosis of ROU was confirmed in 700, and the diagnosis of BID was established in 101 according to the International Study Group criteria. The prevalence rate of BID was estimated as 42/10,000 (95% Cl, 34-51/10,000) in Istanbul, Turkey. Conclusions This survey conducted in Istanbul, the largest cosmopolitan city in Turkey with immigrants from all over the country, has a larger sample size than other previous studies, and therefore the reported prevalence rate of BID has a more acceptable confidence interval. This study aids in the estimation of the prevalence of BID in Turkey, and supports previous findings that Turkey has the highest prevalence rate of the disease in the world.
Açıklama
Anahtar Kelimeler
Kaynak
International Journal of Dermatology
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
42
Sayı
Künye
Azizlerli, G., Köse, A. A., Sarıca, R., Gül, A., Tutkun, İ. T., Kulaç, M., Tunç, R., Urgancıoğlu, M., Dişçi, R., (2003). Prevalence of Behcet's Disease in Istanbul, Turkey. International Journal of Dermatology, (42), 803-806. Doi: 10.1046/j.1365-4362.2003.01893.x
