Prevalence of Behcet's Disease in Istanbul, Turkey

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dc.contributor.authorAzizlerli, Gülsevim
dc.contributor.authorKöse, Afet Akdağ
dc.contributor.authorSarıca, Rıfkiye
dc.contributor.authorGül, Ahmet
dc.contributor.authorTutkun, İlknur Tuğal
dc.contributor.authorKulaç, Mustafa
dc.contributor.authorTunç, Recep
dc.contributor.authorUrgancıoğlu, Meri
dc.contributor.authorDişçi, Rian
dc.date.accessioned2020-03-26T16:45:59Z
dc.date.available2020-03-26T16:45:59Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground The prevalence of Behcet's disease (BID) is much higher in countries along the ancient Silk Route, extending from Japan to Mediterranean countries including Turkey, than in northern Europe and the USA. Three previous epidemiologic surveys have been carried out in different regions of Turkey. Patients and methods This study investigated the cross-sectional prevalence of BID in individuals aged > 12 years in Istanbul, Turkey, in two stages. The first stage aimed to identify individuals with recurrent oral ulcers (ROUs) by visiting them in their homes, and the second stage aimed to further examine those with ROUs for the presence of other BID-related manifestations under hospital conditions. The sample size was determined to be 24,000 with an expected BID prevalence rate of 1/1000 and a sampling error of 4/10,000, with a 95% confidence interval (CI) of 6-14/10,000. The number of individuals to be screened in each district was determined in proportion to the population of all districts in Istanbul. Results The standard questionnaire was applied to a total of 23,986 individuals at their homes. A history of ROU was recorded in 2289 individuals (9.5%), and a previous diagnosis of BID was recorded in 47. The diagnosis of ROU was confirmed in 700, and the diagnosis of BID was established in 101 according to the International Study Group criteria. The prevalence rate of BID was estimated as 42/10,000 (95% Cl, 34-51/10,000) in Istanbul, Turkey. Conclusions This survey conducted in Istanbul, the largest cosmopolitan city in Turkey with immigrants from all over the country, has a larger sample size than other previous studies, and therefore the reported prevalence rate of BID has a more acceptable confidence interval. This study aids in the estimation of the prevalence of BID in Turkey, and supports previous findings that Turkey has the highest prevalence rate of the disease in the world.en_US
dc.identifier.citationAzizlerli, G., Köse, A. A., Sarıca, R., Gül, A., Tutkun, İ. T., Kulaç, M., Tunç, R., Urgancıoğlu, M., Dişçi, R., (2003). Prevalence of Behcet's Disease in Istanbul, Turkey. International Journal of Dermatology, (42), 803-806. Doi: 10.1046/j.1365-4362.2003.01893.x
dc.identifier.doi10.1046/j.1365-4362.2003.01893.xen_US
dc.identifier.endpage806en_US
dc.identifier.issn0011-9059en_US
dc.identifier.pmid1452-1694en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage803en_US
dc.identifier.urihttps://dx.doi.org/10.1046/j.1365-4362.2003.01893.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18536
dc.identifier.volume42en_US
dc.identifier.wosWOS:000186078600006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofInternational Journal of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titlePrevalence of Behcet's Disease in Istanbul, Turkeyen_US
dc.typeArticleen_US

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