Heart-type fatty acid binding protein level as a tool in ıdentification of early cardiac effects of diabetic ketoacidosis

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dc.contributor.authorYılmaz, Fatma Hilal
dc.contributor.authorYuca, Sevil Arı
dc.contributor.authorVatansev, Hüsamettin
dc.contributor.authorCimbek, Emine Ayça
dc.contributor.authorŞen, Yasar
dc.contributor.authorYılmaz, Isa
dc.contributor.authorAkyürek, Fikret
dc.date.accessioned2020-03-26T19:41:49Z
dc.date.available2020-03-26T19:41:49Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: This study aimed to measure the serum levels of heart-type fatty acid binding protein (H-FABP) in patients presenting with diabetic ketoacidosis (DKA) and diabetic ketosis (DK) and to determine its role in identifying early-period cardiac ischemia. Methods: This prospective study included 35 patients diagnosed with DKA, 20 patients diagnosed with DK, and 20 control subjects. H-FABP, creatine kinase-MB (CK-MB), and troponin I levels were investigated at presentation in patients with DKA and DK and in the control group. H-FABP values were measured again after acidosis correction in the DKA patients. Results: No statistically significant differences were found with respect to troponin I and CK-MB within the groups. The H-FABP values of DKA patients at presentation were found to be significantly higher than those of DK patients and the control group (p = 0.015). The H-FABP value of the DKA group was also found to be significantly higher than the value at hour 36 after acidosis correction (p = 0.0001). Conclusion: We would like to propose H-FABP as a potential marker for indicating myocardial ischemia.en_US
dc.description.sponsorshipSelcuk UniversitySelcuk University [13102033]en_US
dc.description.sponsorshipSelcuk University Scientific Research Project Coordinator-Project No: 13102033.en_US
dc.identifier.citationYılmaz, F. H., Yuca, S. A., Vatansev, H., Cimbek, E. A., Şen, Y., Yılmaz, İ., Akyürek, F., Arslan, D., Çimen, D., Yorulmaz, A. (2017). Heart-Type Fatty Acid Binding Protein Level as a Tool in Identification of Early Cardiac Effects of Diabetic Ketoacidosis. Journal of Clinical Research in Pediatric Endocrinology, 9(2), 118-123.
dc.identifier.doi10.4274/jcrpe.3961en_US
dc.identifier.endpage123en_US
dc.identifier.issn1308-5727en_US
dc.identifier.issn1308-5735en_US
dc.identifier.issue2en_US
dc.identifier.pmid28077344en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage118en_US
dc.identifier.urihttps://dx.doi.org/10.4274/jcrpe.3961
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35165
dc.identifier.volume9en_US
dc.identifier.wosWOS:000406446700005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYılmaz, Fatma Hilal
dc.institutionauthorYuca, Sevil Arı
dc.institutionauthorVatansev, Hüsamettin
dc.institutionauthorŞen, Yasar
dc.language.isoenen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.ispartofJournal of Clinical Research in Pediatric Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHeart-type fatty acid binding proteinen_US
dc.subjectchilden_US
dc.subjectdiabetic ketoacidosisen_US
dc.titleHeart-type fatty acid binding protein level as a tool in ıdentification of early cardiac effects of diabetic ketoacidosisen_US
dc.typeArticleen_US

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