Medicinal plants and natural products used in cataract management
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
FRONTIERS MEDIA SA
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Cataract is the leading reason of blindness worldwide and is defined by the presence of any lens opacities or loss of transparency. The most common symptoms of cataract are impaired vision, decreased contrast sensitivity, color disturbance, and glare. Oxidative stress is among the main mechanisms involved in the development of age-related cataract. Surgery through phacoemulsification and intraocular lens implantation is the most effective method for cataract treatment, however, there are chances of serious complications and irreversible loss of vision associated with the surgery. Natural compounds consisting of antioxidant or anti-inflammatory secondary metabolites can serve as potential leads for anticataract agents. In this review, we tried to document medicinal plants and plant-based natural products used for cataract treatment worldwide, which are gathered from available ethnopharmacological/ethnobotanical data. We have extensively explored a number of recognized databases like Scifinder, PubMed, Science Direct, Google Scholar, and Scopus by using keywords and phrases such as "cataract", "blindness", "traditional medicine", "ethnopharmacology", "ethnobotany", "herbs", "medicinal plants", or other relevant terms, and summarized the plants/phytoconstituents that are evaluated in different models of cataract and also tabulated 44 plants that are traditionally used in cataract in various folklore medical practices. Moreover, we also categorized the plants according to scientific studies carried out in different cataract models with their mechanisms of action.
Açıklama
Anahtar Kelimeler
medicinal plants, natural products, cataract, antioxidant, aldose reductase, lens opacity, MAPK
Kaynak
FRONTIERS IN PHARMACOLOGY
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
10
Sayı
Künye
Tewari, D., Samoilă, O., Gocan, D., Mocan, A., Moldovan, C., Devkota, H. P., Atanasov, A. G., Zengin, G., Echeverria, J., Vodnar, D. C., Szabo, B., Crişan, G. (2019). Medicinal Plants And Natural Products Used İn Cataract Management. Frontiers İn Pharmacology, 10, 466.
