Serum Ischemia-Modified Albumin Levels in an Experimental Acute Mesenteric Ischemia Model
dc.contributor.author | Dündar, Zerrin Defne | |
dc.contributor.author | Cander, Başar | |
dc.contributor.author | Gül, Mehmet | |
dc.contributor.author | Uçar Karabulut, Keziban | |
dc.contributor.author | Girişgin, Sadık | |
dc.date.accessioned | 2020-03-26T18:04:59Z | |
dc.date.available | 2020-03-26T18:04:59Z | |
dc.date.issued | 2010 | |
dc.department | Selçuk Üniversitesi | en_US |
dc.description.abstract | Objectives: This experimental study aimed to assess the changes in the levels of serum ischemia-modified albumin (IMA) and interleukin-6 (IL-6) by time in cases of acute mesenteric ischemia due to superior mesenteric artery occlusion. Methods: Twenty-one New Zealand rabbits were randomly divided into three groups. Blood samples were collected at hours 0, 1, 3, and 6 from animals in a control group; a sham group following a simple laparotomy; and in an ischemia group following superior mesenteric artery ligation. All blood samples were analyzed for serum IMA and IL-6 levels, and then the time-dependent changes of biomarkers were investigated. Results: The serum IMA levels of the ischemia group at hours 3 and 6 were significantly higher than those of the control and sham groups (hour 3, p = 0.017; hour 6, p = 0.001). The increase in serum IL-6 levels in the ischemia group at hours 1, 3, and 6 compared to the control and sham groups was also significant (hour 1, p = 0.002; hour 3, p = 0.003; hour 6, p = 0.003). Conclusions: IMA may be helpful as a marker in the diagnosis of acute mesenteric ischemia; however, its diagnostic value and use as a routine biochemical test should be assessed in further studies. | en_US |
dc.description.sponsorship | Selcuk University Scientific Research CommitteeSelcuk University | en_US |
dc.description.sponsorship | This study was supported by the Selcuk University Scientific Research Committee. | en_US |
dc.identifier.citation | Dündar, Z. D., Cander, B., Gül, M., Uçar Karabulut, K., Girişgin, S., (2010). Serum Ischemia-Modified Albumin Levels in an Experimental Acute Mesenteric Ischemia Model. Academic Emergency Medicine, 17(11), 1233-1238. Doi: 10.1111/j.1553-2712.2010.00916.x | |
dc.identifier.doi | 10.1111/j.1553-2712.2010.00916.x | en_US |
dc.identifier.endpage | 1238 | en_US |
dc.identifier.issn | 1069-6563 | en_US |
dc.identifier.issn | 1553-2712 | en_US |
dc.identifier.issue | 11 | en_US |
dc.identifier.pmid | 21175522 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | 1233 | en_US |
dc.identifier.uri | https://dx.doi.org/10.1111/j.1553-2712.2010.00916.x | |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/25257 | |
dc.identifier.volume | 17 | en_US |
dc.identifier.wos | WOS:000283945100016 | en_US |
dc.identifier.wosquality | Q1 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.institutionauthor | Dündar, Zerrin Defne | |
dc.institutionauthor | Cander, Başar | |
dc.institutionauthor | Gül, Mehmet | |
dc.institutionauthor | Uçar Karabulut, Keziban | |
dc.institutionauthor | Girişgin, Sadık | |
dc.language.iso | en | en_US |
dc.publisher | Wiley | en_US |
dc.relation.ispartof | Academic Emergency Medicine | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.title | Serum Ischemia-Modified Albumin Levels in an Experimental Acute Mesenteric Ischemia Model | en_US |
dc.type | Article | en_US |
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