Angiosarcoma of the Submandibular Salivary Gland: Case Report and Review of the Literature

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dc.contributor.authorÜlkü, Çağatay Han
dc.contributor.authorCenik, Ziya
dc.contributor.authorAvunduk, Mustafa
dc.contributor.authorArbağ, Hamdi
dc.date.accessioned2020-03-26T16:45:26Z
dc.date.available2020-03-26T16:45:26Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives-The purpose of this report is to describe an example of angiosarcoma (AS) of the submandibular salivary gland. The clinical and immunohistopathologic features of these lesions are also reviewed. Material and Methods-A 17-year-old male high school student was admitted to our clinic with a 1-year history of a slow growing, tender mass in the left submandibular region. Physical examination on initial presentation revealed a diffuse soft tissue mass 6 cm in diameter involving the left submandibular region. MRI analysis revealed a mass located superolateral to the submandibular salivary gland, measuring 4.0 x 2.0 cm(2). The mass was excised completely together with the left submandibular salivary gland. Histopathologic analysis led to a diagnosis of AS. Immunohistochemical studies were also used to determine endothelial cell differentiation. Owing to the lateralized nature of the lesion, a left functional neck dissection was performed and postoperative radiotherapy was planned. Results-AS is a malignant tumor of endothelial cell origin that may occur in any region of the body. The commonest sites include the extremities and the retroperitoneal space, with only 4% of AS tumors arising in the head and neck area. The submandibular salivary gland is an extremely rare location for this tumor. Based on a literature review, this case report represents only the second reported case of AS of the submandibular salivary gland. Conclusions-In most cases, radical surgery and postoperative radiotherapy are advocated to treat patients with AS tumors, with lymph node clearance recommended in cases of lateralized lesions. In some patients, distant metastasis may occur after many years, which necessitates long-term follow-up. The prognosis is poor in most cases of AS.en_US
dc.identifier.citationÜlkü, Ç. H., Cenik, Z., Avunduk, M., Arbağ, H., (2003). Angiosarcoma of the Submandibular Salivary Gland: Case Report and Review of the Literature. Acta Oto-Laryngologica, 123(3), 440-443. Doi: 10.1080/00016480310001240
dc.identifier.doi10.1080/00016480310001240en_US
dc.identifier.endpage443en_US
dc.identifier.issn0001-6489en_US
dc.identifier.issue3en_US
dc.identifier.pmid12737304en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage440en_US
dc.identifier.urihttps://dx.doi.org/10.1080/00016480310001240
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18372
dc.identifier.volume123en_US
dc.identifier.wosWOS:000182665700018en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis asen_US
dc.relation.ispartofActa Oto-Laryngologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleAngiosarcoma of the Submandibular Salivary Gland: Case Report and Review of the Literatureen_US
dc.typeArticleen_US

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