Pregnancy-associated plasma protein A and procalcitonin as markers of myocardial injury in patients with acute coronary syndrome
dc.contributor.author | Bayır, Ayşegül | |
dc.contributor.author | Kara, Hasan | |
dc.contributor.author | Kıyıcı, Aysel | |
dc.contributor.author | Öztürk, Bahadır | |
dc.contributor.author | Sivrikaya, Abdullah | |
dc.contributor.author | Akyürek, Fikret | |
dc.date.accessioned | 2020-03-26T19:06:43Z | |
dc.date.available | 2020-03-26T19:06:43Z | |
dc.date.issued | 2015 | |
dc.department | Selçuk Üniversitesi | en_US |
dc.description.abstract | Background/aim: To evaluate pregnancy-associated plasma protein A (PAPP-A), ischemia-modified albumin (IMA), procalcitonin, and troponin I levels as diagnostic markers of acute coronary syndrome in patients admitted to the emergency department. Materials and methods: The serum PAPP-A, IMA, procalcitonin, and troponin I levels were measured in 100 patients with acute coronary syndrome admitted to the emergency department and 100 healthy control subjects. Results: Patients with acute coronary syndrome had significantly greater mean serum PAPP-A (patients, 10 +/- 10 mIU/L; control subjects, 6 +/- 10 mIU/L; P <= 0.001), procalcitonin (patients, 2 +/- 10 mu g/L; control subjects, 0.4 +/- 2 mu g/L; P <= 0.001), and troponin I levels (patients, 6 +/- 8 mu g/L; control subjects, 0.2 +/- 0.3 mu g/L; P <= 0.001) than control subjects. There was no difference in mean IMA levels between patients and control subjects. There were no significant correlations between PAPP-A levels and IMA, procalcitonin, or troponin I levels in patients with acute coronary syndrome. Conclusion: The PAPP-A, procalcitonin, and troponin I levels were increased in patients with acute coronary syndrome. Therefore, elevated PAPP-A and procalcitonin levels, in addition to troponin I levels, may be useful markers of myocardial injury on admission to the emergency department. | en_US |
dc.description.sponsorship | Selcuk Universitesi Bilimsel Arastirma Projeleri KoordinatorluguSelcuk University | en_US |
dc.description.sponsorship | This study was supported by the Selcuk Universitesi Bilimsel Arastirma Projeleri Koordinatorlugu. | en_US |
dc.identifier.doi | 10.3906/sag-1311-55 | en_US |
dc.identifier.endpage | 163 | en_US |
dc.identifier.issn | 1300-0144 | en_US |
dc.identifier.issn | 1303-6165 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.pmid | 25790546 | en_US |
dc.identifier.scopusquality | Q3 | en_US |
dc.identifier.startpage | 159 | en_US |
dc.identifier.uri | https://dx.doi.org/10.3906/sag-1311-55 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/32451 | |
dc.identifier.volume | 45 | en_US |
dc.identifier.wos | WOS:000347840000025 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | TR-Dizin | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY | en_US |
dc.relation.ispartof | TURKISH JOURNAL OF MEDICAL SCIENCES | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.subject | Diagnosis | en_US |
dc.subject | emergency department | en_US |
dc.subject | heart | en_US |
dc.subject | infarction | en_US |
dc.subject | PAPP-A | en_US |
dc.subject | troponin I | en_US |
dc.title | Pregnancy-associated plasma protein A and procalcitonin as markers of myocardial injury in patients with acute coronary syndrome | en_US |
dc.type | Article | en_US |