Pregnancy-associated plasma protein A and procalcitonin as markers of myocardial injury in patients with acute coronary syndrome

dc.contributor.authorBayır, Ayşegül
dc.contributor.authorKara, Hasan
dc.contributor.authorKıyıcı, Aysel
dc.contributor.authorÖztürk, Bahadır
dc.contributor.authorSivrikaya, Abdullah
dc.contributor.authorAkyürek, Fikret
dc.date.accessioned2020-03-26T19:06:43Z
dc.date.available2020-03-26T19:06:43Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground/aim: To evaluate pregnancy-associated plasma protein A (PAPP-A), ischemia-modified albumin (IMA), procalcitonin, and troponin I levels as diagnostic markers of acute coronary syndrome in patients admitted to the emergency department. Materials and methods: The serum PAPP-A, IMA, procalcitonin, and troponin I levels were measured in 100 patients with acute coronary syndrome admitted to the emergency department and 100 healthy control subjects. Results: Patients with acute coronary syndrome had significantly greater mean serum PAPP-A (patients, 10 +/- 10 mIU/L; control subjects, 6 +/- 10 mIU/L; P <= 0.001), procalcitonin (patients, 2 +/- 10 mu g/L; control subjects, 0.4 +/- 2 mu g/L; P <= 0.001), and troponin I levels (patients, 6 +/- 8 mu g/L; control subjects, 0.2 +/- 0.3 mu g/L; P <= 0.001) than control subjects. There was no difference in mean IMA levels between patients and control subjects. There were no significant correlations between PAPP-A levels and IMA, procalcitonin, or troponin I levels in patients with acute coronary syndrome. Conclusion: The PAPP-A, procalcitonin, and troponin I levels were increased in patients with acute coronary syndrome. Therefore, elevated PAPP-A and procalcitonin levels, in addition to troponin I levels, may be useful markers of myocardial injury on admission to the emergency department.en_US
dc.description.sponsorshipSelcuk Universitesi Bilimsel Arastirma Projeleri KoordinatorluguSelcuk Universityen_US
dc.description.sponsorshipThis study was supported by the Selcuk Universitesi Bilimsel Arastirma Projeleri Koordinatorlugu.en_US
dc.identifier.doi10.3906/sag-1311-55en_US
dc.identifier.endpage163en_US
dc.identifier.issn1300-0144en_US
dc.identifier.issn1303-6165en_US
dc.identifier.issue1en_US
dc.identifier.pmid25790546en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage159en_US
dc.identifier.urihttps://dx.doi.org/10.3906/sag-1311-55
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32451
dc.identifier.volume45en_US
dc.identifier.wosWOS:000347840000025en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEYen_US
dc.relation.ispartofTURKISH JOURNAL OF MEDICAL SCIENCESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDiagnosisen_US
dc.subjectemergency departmenten_US
dc.subjecthearten_US
dc.subjectinfarctionen_US
dc.subjectPAPP-Aen_US
dc.subjecttroponin Ien_US
dc.titlePregnancy-associated plasma protein A and procalcitonin as markers of myocardial injury in patients with acute coronary syndromeen_US
dc.typeArticleen_US

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