Quantitative analysis of retinal microcirculation in optical coherence tomography angiography in cases with Behcet's disease without ocular involvement

Yükleniyor...
Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

SPRINGER

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

PurposeTo evaluate the retinal vascular plexus and choriocapillaris structures in patients with non-ocular Behcet's disease (BD) using optical coherence tomography angiography (OCTA).MethodsThe study included 42 eyes of non-ocular BD patients (study group) and 40 eyes of 20 healthy subjects (control group). Flow area (mm(2)), mean vascular density (VD) (%) and foveal avascular zone (FAZ) (mm(2)) were measured using OCTA (Optovue Inc., Fremont, CA, USA). Subfoveal choroidal thickness (CT) (mu m) and central macular thickness (CMT) (mu m) measurements were also performed.ResultsThe mean superficial capillary plexus, deep capillary plexus and choriocapillaris flow area values were found to be significantly lower in the study group than in the control group (p<0.001, p<0.001, p=0.008, respectively). In respect of mean VD, a statistically significant difference was determined between the study and control groups in both superficial and deep VD (p<0.001). No statistically significant difference was found out between the groups in respect of superficial FAZ, deep FAZ and CMT (p=0.165, p=0.477, p=0.457, respectively). The subfoveal CT was also measured to be significantly thicker in the study group than in the control group (p<0.001).ConclusionThe results obtained with OCTA revealed that there could be both retinal and choroidal involvement in non-ocular BD patients before the emergence of evident clinical findings.

Açıklama

Anahtar Kelimeler

Vascular density, Flow area, Non-flow area, Non-ocular Behcet's disease, Optical coherence tomography angiography (OCTA)

Kaynak

INTERNATIONAL OPHTHALMOLOGY

WoS Q Değeri

Q4

Scopus Q Değeri

Q2

Cilt

39

Sayı

10

Künye

Çömez, A., Beyoğlu, A., Karaküçük, Y. (2019). Quantitative Analysis Of Retinal Microcirculation İn Optical Coherence Tomography Angiography İn Cases With Behçet’s Disease Without Ocular İnvolvement. International Ophthalmology, 39,(10), 2213-2221.