Quantitative analysis of retinal microcirculation in optical coherence tomography angiography in cases with Behcet's disease without ocular involvement

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dc.contributor.authorComez, Aysegul
dc.contributor.authorBeyoglu, Abdullah
dc.contributor.authorKarakucuk, Yalcin
dc.date.accessioned2020-03-26T20:19:12Z
dc.date.available2020-03-26T20:19:12Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurposeTo evaluate the retinal vascular plexus and choriocapillaris structures in patients with non-ocular Behcet's disease (BD) using optical coherence tomography angiography (OCTA).MethodsThe study included 42 eyes of non-ocular BD patients (study group) and 40 eyes of 20 healthy subjects (control group). Flow area (mm(2)), mean vascular density (VD) (%) and foveal avascular zone (FAZ) (mm(2)) were measured using OCTA (Optovue Inc., Fremont, CA, USA). Subfoveal choroidal thickness (CT) (mu m) and central macular thickness (CMT) (mu m) measurements were also performed.ResultsThe mean superficial capillary plexus, deep capillary plexus and choriocapillaris flow area values were found to be significantly lower in the study group than in the control group (p<0.001, p<0.001, p=0.008, respectively). In respect of mean VD, a statistically significant difference was determined between the study and control groups in both superficial and deep VD (p<0.001). No statistically significant difference was found out between the groups in respect of superficial FAZ, deep FAZ and CMT (p=0.165, p=0.477, p=0.457, respectively). The subfoveal CT was also measured to be significantly thicker in the study group than in the control group (p<0.001).ConclusionThe results obtained with OCTA revealed that there could be both retinal and choroidal involvement in non-ocular BD patients before the emergence of evident clinical findings.en_US
dc.identifier.citationÇömez, A., Beyoğlu, A., Karaküçük, Y. (2019). Quantitative Analysis Of Retinal Microcirculation İn Optical Coherence Tomography Angiography İn Cases With Behçet’s Disease Without Ocular İnvolvement. International Ophthalmology, 39,(10), 2213-2221.
dc.identifier.doi10.1007/s10792-018-1059-zen_US
dc.identifier.endpage2221en_US
dc.identifier.issn0165-5701en_US
dc.identifier.issn1573-2630en_US
dc.identifier.issue10en_US
dc.identifier.pmid30875015en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2213en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s10792-018-1059-z
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38143
dc.identifier.volume39en_US
dc.identifier.wosWOS:000491942400009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKarakucuk, Yalcin
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofINTERNATIONAL OPHTHALMOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectVascular densityen_US
dc.subjectFlow areaen_US
dc.subjectNon-flow areaen_US
dc.subjectNon-ocular Behcet's diseaseen_US
dc.subjectOptical coherence tomography angiography (OCTA)en_US
dc.titleQuantitative analysis of retinal microcirculation in optical coherence tomography angiography in cases with Behcet's disease without ocular involvementen_US
dc.typeArticleen_US

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