Bilateral Cytomegalovirus Retinitis in a Child with Rhabdomyosarcoma
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
KARE PUBL
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Reactivation of cytomegalovirus (CMV) leading to retinitis has been commonly reported in association with human immunodeficiency virus (HIV) infection or iatrogenic suppression of the immune system, including transplant recipients. Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in the pediatric age group, and alveolar histology is associated with unfavorable outcome. Presently described is case of RMS with alveolar histology in a 12-year-old male who developed CMV bilateral retinitis during prolonged period of neutropenic fever after 40 weeks of chemotherapy. He was diagnosed based on CMV-DNA polymerase chain reaction in blood and urine samples, and responded well to intravenous gancyclovir treatment. A high index of suspicion for reactivation of CMV leading to retinitis should be maintained and, if needed, investigated, not only in patients with HIV infection or transplant recipients, but also all patients who are iatrogenically immunosuppressed, including those who experience prolonged neutropenic fever due to lengthy courses of radiotherapy and chemotherapy.
Açıklama
Anahtar Kelimeler
Chemoradiotherapy, cytomegaloviral retinitis, neutropenia, rhabdomyosarcoma
Kaynak
TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
32
Sayı
1
