Bilateral Cytomegalovirus Retinitis in a Child with Rhabdomyosarcoma

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dc.contributor.authorZulfikar, Osman Bulent
dc.contributor.authorEmiroglu, Halil Haldun
dc.contributor.authorKebudi, Rejin
dc.contributor.authorEmiroglu, Melike
dc.contributor.authorTuncer, Samuray
dc.date.accessioned2020-03-26T19:34:05Z
dc.date.available2020-03-26T19:34:05Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractReactivation of cytomegalovirus (CMV) leading to retinitis has been commonly reported in association with human immunodeficiency virus (HIV) infection or iatrogenic suppression of the immune system, including transplant recipients. Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in the pediatric age group, and alveolar histology is associated with unfavorable outcome. Presently described is case of RMS with alveolar histology in a 12-year-old male who developed CMV bilateral retinitis during prolonged period of neutropenic fever after 40 weeks of chemotherapy. He was diagnosed based on CMV-DNA polymerase chain reaction in blood and urine samples, and responded well to intravenous gancyclovir treatment. A high index of suspicion for reactivation of CMV leading to retinitis should be maintained and, if needed, investigated, not only in patients with HIV infection or transplant recipients, but also all patients who are iatrogenically immunosuppressed, including those who experience prolonged neutropenic fever due to lengthy courses of radiotherapy and chemotherapy.en_US
dc.identifier.doi10.5505/tjo.2017.1552en_US
dc.identifier.endpage34en_US
dc.identifier.issn1300-7467en_US
dc.identifier.issue1en_US
dc.identifier.pmid#YOKen_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage31en_US
dc.identifier.urihttps://dx.doi.org/10.5505/tjo.2017.1552
dc.identifier.urihttps://hdl.handle.net/20.500.12395/34837
dc.identifier.volume32en_US
dc.identifier.wosWOS:000424784400006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherKARE PUBLen_US
dc.relation.ispartofTURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectChemoradiotherapyen_US
dc.subjectcytomegaloviral retinitisen_US
dc.subjectneutropeniaen_US
dc.subjectrhabdomyosarcomaen_US
dc.titleBilateral Cytomegalovirus Retinitis in a Child with Rhabdomyosarcomaen_US
dc.typeArticleen_US

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