The distribution of pas-positive uterine natural killer (unk) cells in the decidua basalis of pregnant mice
Yükleniyor...
Dosyalar
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
KAFKAS UNIV, VETERINER FAKULTESI DERGISI
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
This study was carried out to determine the distribution of uterine natural killer (uNK) cells having periodic-acid Schiff (PAS) positive granules in the decidua basalis in pregnant mice. For this purpose, mice at 12-14 weeks of age were divided into four groups as nonpregnant control, and at the middle of the first, second, and the third week of the pregnancy, corresponding to early, middle, and late (3rd, 10th, and 17th days of pregnancy) gestational stages respectively (n=6 for each group). After placentation, it was identified four different regions as metrial region (MLAp; mesometrial lymphoid aggregate of pregnancy), decidua basalis, junctional zone and labyrinth zone in mice. It was observed trophoblast giant cells between decidua basalis and junctional zone. The number of PAS-positive uNK cells was found as 5 in 10.000 mu m(2) in endometrium of control animals while it was determined as 26.5 number/10.000 mu m(2) in decidua basalis at early gestational period. The highest PAS-positive uNK cell numbers (56 number/10.000 mu m(2)) were detected at the mid-gestational period in decidua basalis. uNK cells were also observed in the lumen of the maternal blood vessels. In mesometrial region, the dilatation of maternal blood vessels and thinning of the media layer was distinct. It was concluded that the number and the distribution of the uNK cells having periodic-acid Schiff (PAS) positive granules was affected by pregnancy.
Açıklama
Anahtar Kelimeler
Mice, PAS, Pregnancy, uNK
Kaynak
KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
21
Sayı
3
Künye
Sur, E., Öznurlu, Y., Özaydın, T., Çelik, İ., Aydın, İ., Kadıralieva, N. (2015). The Distribution of PAS-Positive Uterine Natural Killer (uNK) Cells in the Decidua Basalis of Pregnant Mice. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 21(3), 405-411.
