The distribution of pas-positive uterine natural killer (unk) cells in the decidua basalis of pregnant mice

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dc.contributor.authorSur, Emrah
dc.contributor.authorOznurlu, Yasemin
dc.contributor.authorOzaydin, Tugba
dc.contributor.authorCelik, Ilhami
dc.contributor.authorAydin, Ibrahim
dc.contributor.authorKadyralieva, Nariste
dc.date.accessioned2020-03-26T19:07:21Z
dc.date.available2020-03-26T19:07:21Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesi, Veteriner Fakültesi, Temel Bilimler Bölümüen_US
dc.description.abstractThis study was carried out to determine the distribution of uterine natural killer (uNK) cells having periodic-acid Schiff (PAS) positive granules in the decidua basalis in pregnant mice. For this purpose, mice at 12-14 weeks of age were divided into four groups as nonpregnant control, and at the middle of the first, second, and the third week of the pregnancy, corresponding to early, middle, and late (3rd, 10th, and 17th days of pregnancy) gestational stages respectively (n=6 for each group). After placentation, it was identified four different regions as metrial region (MLAp; mesometrial lymphoid aggregate of pregnancy), decidua basalis, junctional zone and labyrinth zone in mice. It was observed trophoblast giant cells between decidua basalis and junctional zone. The number of PAS-positive uNK cells was found as 5 in 10.000 mu m(2) in endometrium of control animals while it was determined as 26.5 number/10.000 mu m(2) in decidua basalis at early gestational period. The highest PAS-positive uNK cell numbers (56 number/10.000 mu m(2)) were detected at the mid-gestational period in decidua basalis. uNK cells were also observed in the lumen of the maternal blood vessels. In mesometrial region, the dilatation of maternal blood vessels and thinning of the media layer was distinct. It was concluded that the number and the distribution of the uNK cells having periodic-acid Schiff (PAS) positive granules was affected by pregnancy.en_US
dc.identifier.citationSur, E., Öznurlu, Y., Özaydın, T., Çelik, İ., Aydın, İ., Kadıralieva, N. (2015). The Distribution of PAS-Positive Uterine Natural Killer (uNK) Cells in the Decidua Basalis of Pregnant Mice. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 21(3), 405-411.
dc.identifier.doi10.9775/kvfd.2014.12718en_US
dc.identifier.endpage411en_US
dc.identifier.issn1300-6045en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage405en_US
dc.identifier.urihttps://dx.doi.org/10.9775/kvfd.2014.12718
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32615
dc.identifier.volume21en_US
dc.identifier.wosWOS:000354410400017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorSur, Emrah
dc.institutionauthorOznurlu, Yasemin
dc.institutionauthorOzaydin, Tugba
dc.institutionauthorCelik, Ilhami
dc.institutionauthorAydin, Ibrahim
dc.language.isotren_US
dc.publisherKAFKAS UNIV, VETERINER FAKULTESI DERGISIen_US
dc.relation.ispartofKAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISIen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectMiceen_US
dc.subjectPASen_US
dc.subjectPregnancyen_US
dc.subjectuNKen_US
dc.titleThe distribution of pas-positive uterine natural killer (unk) cells in the decidua basalis of pregnant miceen_US
dc.typeArticleen_US

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