Long-term outcomes in pediatric appendiceal carcinoids: Turkey experience

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dc.contributor.authorAkova, Fatih
dc.contributor.authorAydın, Emrah
dc.contributor.authorEray, Y. Nur
dc.contributor.authorToksoy, Nurseli
dc.contributor.authorYalçın, Şenay
dc.contributor.authorAltınay, Serdar
dc.contributor.authorTetikkurt, Ümit Seza
dc.date.accessioned2020-03-26T19:54:35Z
dc.date.available2020-03-26T19:54:35Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe tendency of non-operative management of appendicitis let us explore the natural history of appendiceal carcinoids, compare them with appendicitis patients, and determine the possibility of deciding the extent of the surgery and post-operative follow-up on behalf of the intraoperative findings. A retrospective review was performed of patients with appendicitis between 2009 and 2017. Of 2781 patients, 10 (0.36%) were diagnosed with appendiceal carcinoids. Sixty percent were female with an average age of 13.101.73. The mean tumor size was 0.97 +/- 0.34cm with 70% located at the tip. Majority had an insular pattern (n=9), six had subserosal fat tissue invasion, one had extension to mesoappendix, one had vascular invasion, and two had lymphatic invasion. The average mitotic index was 3.20 +/- 1.40/50HPF, and Ki 67 activity was 3 +/- 1.7%. The mean follow-up period was 66.40 +/- 25.92months. Patients were further evaluated with ultrasonography (n=10), CT (n=3), and MRI (n=10). Serum markers including chromogranin (n=9), NSE (n=6), and 5-HIAA (n=6) were normal. None required further treatment and had any symptoms of carcinoid syndromes or recurrences post-operatively.p id=Par2 Conclusion: Other than appendectomy, no additional surgery or follow-up is required in appendiceal carcinoids less than 1.5cm in size, regardless of the lymphoid or vascular invasion.en_US
dc.identifier.doi10.1007/s00431-018-3258-zen_US
dc.identifier.endpage1850en_US
dc.identifier.issn0340-6199en_US
dc.identifier.issn1432-1076en_US
dc.identifier.issue12en_US
dc.identifier.pmid30255450en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1845en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s00431-018-3258-z
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36758
dc.identifier.volume177en_US
dc.identifier.wosWOS:000450003400014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofEUROPEAN JOURNAL OF PEDIATRICSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAppendicitisen_US
dc.subjectCarcinoid tumoren_US
dc.subjectChildrenen_US
dc.subjectNeuroendocrine tumorsen_US
dc.titleLong-term outcomes in pediatric appendiceal carcinoids: Turkey experienceen_US
dc.typeArticleen_US

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