Interleukin-1 Beta and Tumour Necrosis Factor-Alpha Levels in Periapical Exudates

dc.contributor.authorAtaoğlu, T.
dc.contributor.authorÜngör, M.
dc.contributor.authorSerpek, B.
dc.contributor.authorHaliloğlu, S.
dc.contributor.authorAtaoğlu, H.
dc.contributor.authorArı, H.
dc.date.accessioned2020-03-26T16:39:13Z
dc.date.available2020-03-26T16:39:13Z
dc.date.issued2002
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim The aim of this study was to determine IL-1beta and TNT-alpha levels in periapical exudates and to evaluate their relationship with clinical and radiological findings. Methodology Periapical exudates were collected from root canals of 3 5 single-rooted teeth using absorbent paper points. IL-1beta and TNT-alpha levels were determined by enzyme-linked immunosorbent assays. The samples were divided into two groups according to the presence or absence of clinical signs including swelling and/or fistula, pain on palpation and/or percussion. and pus discharge from canals. Periapical exudate samples were divided into two groups according to size of periapical radiolucent area. Results The mean concentration of IL-1beta (72.79 ng mL(-2)) in periapical exudates was approximately 12-fold higher than TNT-alpha (6.17 ng mL(-1)), There was no significant correlation between these cytokines (P>0.05). IL-1beta levels in canals with larger radiolucent areas (long axis greater than or equal to1 cm) were significantly higher than those with small areas (P<0.05). There was a tendency toward higher levels of IL-1&beta; in groups with clinical signs, but the differences were not significant (P>0.05). Conclusions Periapical exudate levels of both cytokines failed to reflect periapical disease state.en_US
dc.identifier.citationAtaoğlu, T., Üngör, M., Serpek, B., Haliloğlu, S., Ataoğlu, H., Arı, H., (2002). Interleukin-1 Beta and Tumour Necrosis Factor-alpha Levels in Periapical Exudates. International Endodontic Journal, 35(2), 181-185. Doi: 10.1046/j.1365-2591.2002.00467.x
dc.identifier.doi10.1046/j.1365-2591.2002.00467.xen_US
dc.identifier.endpage185en_US
dc.identifier.issn0143-2885en_US
dc.identifier.issue2en_US
dc.identifier.pmid11843974en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage181en_US
dc.identifier.urihttps://dx.doi.org/10.1046/j.1365-2591.2002.00467.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17979
dc.identifier.volume35en_US
dc.identifier.wosWOS:000173921100008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAtaoğlu, T.
dc.institutionauthorÜngör, M.
dc.institutionauthorSerpek, B.
dc.institutionauthorAtaoğlu, H.
dc.institutionauthorArı, H.
dc.language.isoenen_US
dc.publisherBLACKWELL PUBLISHING LTDen_US
dc.relation.ispartofInternational Endodontic Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectinterleukin-1 betaen_US
dc.subjectperiapical diseasesen_US
dc.subjectperiapical granulomaen_US
dc.subjecttumour necrosis factor-alphaen_US
dc.titleInterleukin-1 Beta and Tumour Necrosis Factor-Alpha Levels in Periapical Exudatesen_US
dc.typeArticleen_US

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