Interleukin-1 Beta and Tumour Necrosis Factor-Alpha Levels in Periapical Exudates
dc.contributor.author | Ataoğlu, T. | |
dc.contributor.author | Üngör, M. | |
dc.contributor.author | Serpek, B. | |
dc.contributor.author | Haliloğlu, S. | |
dc.contributor.author | Ataoğlu, H. | |
dc.contributor.author | Arı, H. | |
dc.date.accessioned | 2020-03-26T16:39:13Z | |
dc.date.available | 2020-03-26T16:39:13Z | |
dc.date.issued | 2002 | |
dc.department | Selçuk Üniversitesi | en_US |
dc.description.abstract | Aim The aim of this study was to determine IL-1beta and TNT-alpha levels in periapical exudates and to evaluate their relationship with clinical and radiological findings. Methodology Periapical exudates were collected from root canals of 3 5 single-rooted teeth using absorbent paper points. IL-1beta and TNT-alpha levels were determined by enzyme-linked immunosorbent assays. The samples were divided into two groups according to the presence or absence of clinical signs including swelling and/or fistula, pain on palpation and/or percussion. and pus discharge from canals. Periapical exudate samples were divided into two groups according to size of periapical radiolucent area. Results The mean concentration of IL-1beta (72.79 ng mL(-2)) in periapical exudates was approximately 12-fold higher than TNT-alpha (6.17 ng mL(-1)), There was no significant correlation between these cytokines (P>0.05). IL-1beta levels in canals with larger radiolucent areas (long axis greater than or equal to1 cm) were significantly higher than those with small areas (P<0.05). There was a tendency toward higher levels of IL-1β in groups with clinical signs, but the differences were not significant (P>0.05). Conclusions Periapical exudate levels of both cytokines failed to reflect periapical disease state. | en_US |
dc.identifier.citation | Ataoğlu, T., Üngör, M., Serpek, B., Haliloğlu, S., Ataoğlu, H., Arı, H., (2002). Interleukin-1 Beta and Tumour Necrosis Factor-alpha Levels in Periapical Exudates. International Endodontic Journal, 35(2), 181-185. Doi: 10.1046/j.1365-2591.2002.00467.x | |
dc.identifier.doi | 10.1046/j.1365-2591.2002.00467.x | en_US |
dc.identifier.endpage | 185 | en_US |
dc.identifier.issn | 0143-2885 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.pmid | 11843974 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | 181 | en_US |
dc.identifier.uri | https://dx.doi.org/10.1046/j.1365-2591.2002.00467.x | |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/17979 | |
dc.identifier.volume | 35 | en_US |
dc.identifier.wos | WOS:000173921100008 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.institutionauthor | Ataoğlu, T. | |
dc.institutionauthor | Üngör, M. | |
dc.institutionauthor | Serpek, B. | |
dc.institutionauthor | Ataoğlu, H. | |
dc.institutionauthor | Arı, H. | |
dc.language.iso | en | en_US |
dc.publisher | BLACKWELL PUBLISHING LTD | en_US |
dc.relation.ispartof | International Endodontic Journal | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.subject | interleukin-1 beta | en_US |
dc.subject | periapical diseases | en_US |
dc.subject | periapical granuloma | en_US |
dc.subject | tumour necrosis factor-alpha | en_US |
dc.title | Interleukin-1 Beta and Tumour Necrosis Factor-Alpha Levels in Periapical Exudates | en_US |
dc.type | Article | en_US |
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