The Relationship Between Epicardial Adipose Tissue and Coronary Artery Calcification in Peritoneal Dialysis Patients

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dc.contributor.authorTürkmen, Kültigin
dc.contributor.authorÖzbek, Orhan
dc.contributor.authorKayıkçıoğlu, Hatice
dc.contributor.authorKayrak, Mehmet
dc.contributor.authorSolak, Yalçın
dc.contributor.authorNayman, Alaaddin
dc.contributor.authorAnıl, Melih
dc.contributor.authorBabur, Hüseyin
dc.contributor.authorTonbul, Halil Zeki
dc.date.accessioned2020-03-26T18:31:50Z
dc.date.available2020-03-26T18:31:50Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Atherosclerosis, endothelial dysfunction, coronary artery calcification (CAC), and left ventricular hypertrophy are the most commonly encountered risk factors in the pathogenesis of cardiovascular disease in end-stage renal disease patients. Epicardial adipose tissue (EAT) is the true visceral fat depot of the heart. The relationship between coronary artery disease and EAT has been shown in healthy subjects and patients with a high risk of coronary artery disease. In the present study, we aimed to investigate the relationship between EAT and CAC in peritoneal dialysis (PD) patients. Patients and Methods: Forty-five PD patients (18 females, 27 males, with a mean age of 50.6 +/- 15 years) and 25 healthy subjects (12 females, 13 males, with a mean age of 52.4 +/- 10.7 years) were enrolled in the study. EAT and CAC score (CACS) measurements were performed by a multidetector computed tomography scanner. Results: EAT of the PD patients was significantly higher than that of the healthy subjects (p = 0.02). When patients were divided into two subgroups (group 1: CACS <= 10, n = 20; group 2: CACS >10, n = 25), EAT was also significantly higher in group 2 patients than in group 1 patients and healthy subjects. Age and EAT were also found to be correlated with CACS >= 10. Conclusion: There is a relationship between the anatomic assessment of coronary artery lesions by multidetector computed tomography and EAT in PD patients. This relationship might be attributed to increased inflammation and proinflammatory cytokines in uremic patients.en_US
dc.identifier.citationTürkmen, K., Özbek, O., Kayıkçıoğlu, H., Kayrak, M., Solak, Y., Nayman, A., Anıl, M., Babur, H., Tonbul, H. Z., (2012). The Relationship Between Epicardial Adipose Tissue and Coronary Artery Calcification in Peritoneal Dialysis Patients. Cardiorenal Medicine, 2(1), 43-51. DOI: 10.1159/000335495
dc.identifier.doi10.1159/000335495en_US
dc.identifier.endpage51en_US
dc.identifier.issn1664-3828en_US
dc.identifier.issn1664-5502en_US
dc.identifier.issue1en_US
dc.identifier.pmid22493602en_US
dc.identifier.startpage43en_US
dc.identifier.urihttps://dx.doi.org/10.1159/000335495
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28551
dc.identifier.volume2en_US
dc.identifier.wosWOS:000312167700006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTürkmen, Kültigin
dc.institutionauthorÖzbek, Orhan
dc.institutionauthorKayıkçıoğlu, Hatice
dc.institutionauthorKayrak, Mehmet
dc.institutionauthorSolak, Yalcin
dc.institutionauthorNayman, Alaaddin
dc.institutionauthorAnıl, Melih
dc.institutionauthorBabur, Hüseyin
dc.institutionauthorTonbul, Halil Zeki
dc.language.isoenen_US
dc.publisherKARGERen_US
dc.relation.ispartofCardiorenal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectPeritoneal Dialysisen_US
dc.subjectEpicardial Adipose Tissueen_US
dc.subjectCoronary Artery Calcificationen_US
dc.subjectEnd-Stage Renal Diseaseen_US
dc.titleThe Relationship Between Epicardial Adipose Tissue and Coronary Artery Calcification in Peritoneal Dialysis Patientsen_US
dc.typeArticleen_US

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