Effect of Lipoprotein Apheresis on Oxidative Stress and Antioxidant Status in Familial Hypercholesterolemic Patients

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dc.contributor.authorKurtoğlu, E.
dc.contributor.authorUğur, A.
dc.contributor.authorGönen, Mustafa Sait
dc.contributor.authorKısakol, G.
dc.date.accessioned2020-03-26T16:45:36Z
dc.date.available2020-03-26T16:45:36Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractExtracorporeal low-density lipoprotein (LDL) apheresis is an established and highly effective therapy for the patients with familial hypercholesterolemia (FH) not adequately responding to diet and drug therapy alone. This study was designed to measure the effect of lipid apheresis on oxidant and antioxidant status in a patient with FH. The levels of plasma lipid peroxidation were determined as thiobarbituric acid-reactive substances. The activities of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) were established in one subject with FH before and after lipid apheresis. The pre- and post lipid apheresis procedures witness a significant decrease in oxidative stress (p<0.05) but the erythrocyte levels of CAT SOD and GPx were unchanged.en_US
dc.identifier.citationKurtoğlu, E., Uğur, A., Gönen, M. S., Kısakol, G., (2003). Effect of Lipoprotein Apheresis on Oxidative Stress and Antioxidant Status in Familial Hypercholesterolemic Patients. International Journal of Artificial Organs, 26(11), 1039-1043.
dc.identifier.endpage1043en_US
dc.identifier.issn0391-3988en_US
dc.identifier.issue11en_US
dc.identifier.pmid14708833en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1039en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18429
dc.identifier.volume26en_US
dc.identifier.wosWOS:000187506500010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKurtoğlu, E.
dc.institutionauthorUğur, A.
dc.institutionauthorGönen, Mustafa Sait
dc.institutionauthorKısakol, G.
dc.language.isoenen_US
dc.publisherWichtig Editoreen_US
dc.relation.ispartofInternational Journal of Artificial Organsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectFamilial Hypercholesterolemiaen_US
dc.subjectLipid Apheresisen_US
dc.subjectOxidative Stressen_US
dc.subjectAntioxidantsen_US
dc.titleEffect of Lipoprotein Apheresis on Oxidative Stress and Antioxidant Status in Familial Hypercholesterolemic Patientsen_US
dc.typeArticleen_US

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