Somatosensory Spinal Cord Evoked Potentials in the Evaluation of the Effect of Dexamethasone in Experimental Spinal Cord Injury

dc.contributor.authorGüney, Önder
dc.contributor.authorAcar, Osman
dc.contributor.authorDemir, Orhan
dc.contributor.authorÜstün, M. Erkan
dc.contributor.authorKocaoğullar, Yalçın
dc.date.accessioned2020-03-26T16:26:19Z
dc.date.available2020-03-26T16:26:19Z
dc.date.issued1998
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractWe studied the effects of high-dose dexamethasone on amplitude and latency values of spinal cord evoked potentials. Thirty-three rabbits were divided into three equal groups. The first group served as the control group, the others received high-dose (2.5 mg/kg) dexamenthasone, the second group I hour prior to and the third group immediately after the induction of a spinal cord trauma in segment T12. The spinal cord evoked potentials were recorded epidurally from T12 segment 5 min before and 5, 30, 60, 90, 120 and 150 min after trauma. Pretreatment with dexamethasone (group II) prevented the latency delay, and later treatment with dexemethasone (group III) prevented the latency delay partially. Our results suggest that when dexamethasone is given prophylactially it prevents latency alteration, while treatment with dexamethasone after lesioning prevents latency alteration partially. From our results we conclude that pretreatment with dexamethasone may involve different mechanisms than were activated in the posttreatment group.en_US
dc.identifier.citationGüney, Ö., Acar, O., Demir, O., Üstün, M. E., Kocaoğullar, Y., (1998). Somatosensory Spinal Cord Evoked Potentials in the Evaluation of the Effect of Dexamethasone in Experimental Spinal Cord Injury. Neurosurgical Review, 21(4), 265-269. DOI:10.1007/BF01105783
dc.identifier.doi10.1007/BF01105783en_US
dc.identifier.endpage269en_US
dc.identifier.issn0344-5607en_US
dc.identifier.issn1437-2320en_US
dc.identifier.issue4en_US
dc.identifier.pmid10068188en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage265en_US
dc.identifier.urihttps://dx.doi.org/10.1007/BF01105783
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16792
dc.identifier.volume21en_US
dc.identifier.wosWOS:000078715800009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGüney, Önder
dc.institutionauthorAcar, Osman
dc.institutionauthorDemir, Orhan
dc.institutionauthorÜstün, M. Erkan
dc.institutionauthorKocaoğullar, Yalçın
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofNeurosurgical Reviewen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDexamethasoneen_US
dc.subjectSomatosensory Evoked Potentialen_US
dc.subjectSpinal Cord Injuryen_US
dc.titleSomatosensory Spinal Cord Evoked Potentials in the Evaluation of the Effect of Dexamethasone in Experimental Spinal Cord Injuryen_US
dc.typeArticleen_US

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