Effects of aflatoxin on AgNOR activity of cells in different regions of kidney, and protective effectiveness of esterified glucomannan in ram

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dc.contributor.authorColakoglu, Fatma
dc.contributor.authorDonmez, Hasan Huseyin
dc.date.accessioned2020-03-26T18:41:40Z
dc.date.available2020-03-26T18:41:40Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesi, Veteriner Fakültesi, Temel Bilimler Bölümüen_US
dc.description.abstractIn this study, the effects of total aflatoxin (AF) given orally on silver-staining nucleolus organizer regions (AgNORs) activity were studied in glomerulus and tubular epithelial cells of kidney in Merino rams. In addition, this study was conducted in order to evaluate the efficacy of an esterified glucomannan (EG) for protection against to aflatoxicosis. As materials, 1 year-old 32 Merino rams were used. Rams were fed through the 92 days. Control group (C) fed with the commercial feed. AF group fed with commercial feed added 250 mu g/day of total AF. EG group fed with commercial feed added 2 g/day of EG daily. AF+EG group fed with commercial feed added 250 mu g/day of total AF and 2 g/day of EG. At the end of the 92nd day the animals were sacrificed, and tissue samples were taken from the kidneys. Whereas ratio of nuclear area of the AgNOR area of cells in examinated regions of kidney was found decreased significantly (P<0.05) in the AF group compared to the control group, AF+EG group was found similar to control group (P>0.05). In conclusion, the adverse effects causing by aflatoxicosis on the kidney AgNOR activity could be ameliorated by adding EG to the ration.en_US
dc.description.sponsorshipSelcuk University Scientific Research Projects (BAP) Coordinating OfficeSelcuk University [09202023]; TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [107O866]en_US
dc.description.sponsorshipThis study forms part of the PhD Thesis of Fatma KAYIKCI COLAKOGLU, for which we thank the "Selcuk University Scientific Research Projects (BAP) Coordinating Office", Project no: 09202023, and TUBITAK, Project No: 107O866, for financial supporten_US
dc.identifier.citationColakoglu, F., Donmez, H. H. (2013). Effects of Aflatoxin on AgNOR Activity of Cells in Different Regions of Kidney, and Protective Effectiveness of Esterified Glucomannan in Ram. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 19(3), 505-509.
dc.identifier.doi10.9775/kvfd.2012.8176en_US
dc.identifier.endpage509en_US
dc.identifier.issn1300-6045en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage505en_US
dc.identifier.urihttps://dx.doi.org/10.9775/kvfd.2012.8176
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29432
dc.identifier.volume19en_US
dc.identifier.wosWOS:000321750600023en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorColakoglu, Fatma
dc.institutionauthorDonmez, Hasan Huseyin
dc.language.isoenen_US
dc.publisherKAFKAS UNIV, VETERINER FAKULTESI DERGISIen_US
dc.relation.ispartofKAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISIen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAflatoxinen_US
dc.subjectAgNORen_US
dc.subjectGlucomannanen_US
dc.subjectKidneyen_US
dc.subjectRamen_US
dc.titleEffects of aflatoxin on AgNOR activity of cells in different regions of kidney, and protective effectiveness of esterified glucomannan in ramen_US
dc.typeArticleen_US

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