Comparison of the Effects of Two Antidepressants on Exercise Performance of the Female Patients With Fibromyalgia
Yükleniyor...
Dosyalar
Tarih
2006
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: To compare the effects of two antidepressants on exercise performance of the female patients with fibromyalgia. Methods: Fifteen patients with fibromyalgia participated in this randomized, double-blind crossover study composed of two trials separated by a 2-week washout phase. The pharmacy randomly assigned patients to two groups: (a) placebo (glucose) in the morning and 25 mg amitriptyline at bedtime or (b) 20 mg fluoxetine in the morning and placebo at bedtime. The VO2max and Wingate anaerobic test were evaluated. Within 24 h after 15-day medication, the tests were repeated. Results: Peak power and fatigue index increased, and VO2max and VT did not change with both fluoxetine and amitriptyline. Mean power significantly increased after fluoxetine but not after amitriptyline. Conclusion: Both amitriptyline administration and fluoxetine administration in patients with fibromyalgia have beneficial effects on anaerobic performance. These effects may be important in life quality of the female patients with fibromyalgia.
Açıklama
Anahtar Kelimeler
antidepressants, exercise, fibromyalgia, life quality, performance
Kaynak
Clinical Rheumatology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
25
Sayı
Künye
Özerbil, Ö., Okudan, N., Gökbel, H., Levendoğlu, F., (2006). Comparison of the Effects of Two Antidepressants on Exercise Performance of the Female Patients With Fibromyalgia. Clinical Rheumatology, (25), 495-497. Doi: 10.1007/s10067-005-0076-2
