Normative values of thymus in healthy children; stiffness by shear wave elastography

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dc.authorid0000-0002-1695-3290
dc.authorid0000-0001-5585-1476
dc.authorid0000-0001-9869-1396
dc.authorid0000-0003-0244-7765
dc.authorid0000-0003-4531-6466
dc.contributor.authorBayramoğlu, Zuhal
dc.contributor.authorÖztürk, Mehmet
dc.contributor.authorÇalışkan, Emine
dc.contributor.authorAyyıldız, Hakan
dc.contributor.authorAdaletli, İbrahim
dc.date.accessioned2020-03-26T20:20:23Z
dc.date.available2020-03-26T20:20:23Z
dc.date.issued2020
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractPURPOSE Thymus grows after birth, reaches maximal size after the first few years and involutes by puberty. Because of the postnatal developmental and involutional duration, we aimed to investigate normal stiffness values of mediastinal thymus by shear wave elastography (SWE) in different age groups of children and discuss imaging findings of thymus. METHODS We prospectively examined 146 children (90 girls, 56 boys) who underwent a thyroid or neck ultrasound examination. All subjects underwent ultrasound and SWE evaluation of mediastinal thymus by parasternal and suprasternal approach. We grouped the subjects based on age as 0 to 2 months, >2 to 6 months, >6 months to 2 years, >2 to 5 years, >5 to 8 years, and greater than 8 years old. We investigated differences of mean shear wave elasticity (kPa) and shear wave velocity (m/s) values among age groups and the association of SWE values with age, body mass index (BMI), height, and weight of the patients. RESULTS Median and range of age, height, weight, and BMI were 24 months (2-84 months), 85 cm (55-120 cm), 12 kg (4.55-22 kg), 15.37 kg/m(2) (13.92-17.51 kg/m(2)), 11 cc (2.64-23.15 cc), respectively. Mean shear wave elasticity of thymus of all participants was 6.76 +/- 1.04 kPa. Differences of mean elasticity values among the age and gender groups were not statistically significant. Thymus elasticity and velocity values showed highly significant negative correlations with age (r=-0.3), height (r=-0.26), weight (r=-0.3) (P < 0.001). CONCLUSION Quantitative evaluation of the thymus by SWE provides normative stiffness values based on age and gender groups. The thymus elasticity decreases with increased age, height, and weight.en_US
dc.identifier.citationBayramoğlu, Z., Öztürk, M., Çalışkan, E., Ayyıldız, H., Adaletli, İ. (2020). Normative Values of Thymus in Healthy Children; Stiffness by Shear Wave Elastography. Diagnostic and Interventional Radiology, 26(2), 147-152.
dc.identifier.doi10.5152/dir.2019.19344en_US
dc.identifier.endpage152en_US
dc.identifier.issn1305-3612en_US
dc.identifier.issue2en_US
dc.identifier.pmid32116221en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage147en_US
dc.identifier.urihttps://dx.doi.org/10.5152/dir.2019.19344
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38576
dc.identifier.volume26en_US
dc.identifier.wosWOS:000518142400012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖztürk, Mehmet.
dc.language.isoenen_US
dc.publisherAVESen_US
dc.relation.ispartofDIAGNOSTIC AND INTERVENTIONAL RADIOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectthymus
dc.subjectNormative values
dc.subjectshear wave elastography
dc.subjectstiffness
dc.titleNormative values of thymus in healthy children; stiffness by shear wave elastographyen_US
dc.typeArticleen_US

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