EFFECTS OF MELATONIN SUPPLEMENTATION ON EXERCISE-INDUCED CHANGES IN CONDUCTION VELOCITY DISTRIBUTIONS
Küçük Resim Yok
Tarih
2009
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
PROUS SCIENCE, SA
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The mammalian nervous system processes complex information to control complex behaviors. Since the speed of transport of information can be a life-saving phenomenon, it is extremely important to stabilize the rate of these processes. This study aims to investigate the protective effects of melatonin supplementation on acute heavy exercise-induced changes in the nerve conduction velocity distributions (CVD). Remodeling of the sciatic nerve due to heavy exercise demonstrates not only on increase in some parameters (rheobase and chronaxie), but also decreases in maximum depolarization, total area under the compound action potential (CAP), fall-down phase of CAP kinetics and speed of the intermediately conducting group. Acute heavy exercise-induced decreases in the contribution of nerve fibers were mainly found between 1.0 and 1.7 interstimulus interval (ISI) values (46-52 m/s). Presupplementotion with melatonin, a powerful antioxidant for nervous tissues, protects the sciatic nerve against off of the aforementioned changes. Presupplementotion not only protects the nerve cells from exercise-induced damage, but also increases the contribution of nerve fibers with conduction velocities of 46-52 m/s.
Açıklama
Anahtar Kelimeler
Sciatic nerve, Acute heavy exercise, Antioxidant, Melatonin, Conduction
Kaynak
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
31
Sayı
3
