EFFECTS OF MELATONIN SUPPLEMENTATION ON EXERCISE-INDUCED CHANGES IN CONDUCTION VELOCITY DISTRIBUTIONS

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dc.contributor.authorAyaz, M.
dc.contributor.authorOkudan, N.
dc.date.accessioned2020-03-26T17:38:29Z
dc.date.available2020-03-26T17:38:29Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe mammalian nervous system processes complex information to control complex behaviors. Since the speed of transport of information can be a life-saving phenomenon, it is extremely important to stabilize the rate of these processes. This study aims to investigate the protective effects of melatonin supplementation on acute heavy exercise-induced changes in the nerve conduction velocity distributions (CVD). Remodeling of the sciatic nerve due to heavy exercise demonstrates not only on increase in some parameters (rheobase and chronaxie), but also decreases in maximum depolarization, total area under the compound action potential (CAP), fall-down phase of CAP kinetics and speed of the intermediately conducting group. Acute heavy exercise-induced decreases in the contribution of nerve fibers were mainly found between 1.0 and 1.7 interstimulus interval (ISI) values (46-52 m/s). Presupplementotion with melatonin, a powerful antioxidant for nervous tissues, protects the sciatic nerve against off of the aforementioned changes. Presupplementotion not only protects the nerve cells from exercise-induced damage, but also increases the contribution of nerve fibers with conduction velocities of 46-52 m/s.en_US
dc.identifier.doi10.1358/mf.2009.31.3.1367703en_US
dc.identifier.endpage156en_US
dc.identifier.issn0379-0355en_US
dc.identifier.issue3en_US
dc.identifier.pmid19536357en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage151en_US
dc.identifier.urihttps://dx.doi.org/10.1358/mf.2009.31.3.1367703
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23491
dc.identifier.volume31en_US
dc.identifier.wosWOS:000267839000001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPROUS SCIENCE, SAen_US
dc.relation.ispartofMETHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectSciatic nerveen_US
dc.subjectAcute heavy exerciseen_US
dc.subjectAntioxidanten_US
dc.subjectMelatoninen_US
dc.subjectConductionen_US
dc.titleEFFECTS OF MELATONIN SUPPLEMENTATION ON EXERCISE-INDUCED CHANGES IN CONDUCTION VELOCITY DISTRIBUTIONSen_US
dc.typeArticleen_US

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