Effects of isotretinoin on the hair cycle
Yükleniyor...
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
WILEY
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background/ ObjectivesIsotretinoin is a synthetic vitamin A agent that affects all of the pathogenic factors that suppress sebum production and play a role in the formation of acne. It is frequently used in the treatment of moderate-severe acne vulgaris. However, there are some mucocutaneous and systemic side effects that limit the use of isotretinoin. In this study, we aimed to determine the effect of isotretinoin on hair growth parameters. Material and MethodsIsotretinoin treatment at 0.5mg/kg per day dose was started to patients with moderate-severe acne vulgaris, and hair growth parameters were evaluated before treatment and after 3months of treatment. Parameters were measured by Fotofinder dermatoscopy device using the TrichoScan Professional program. ResultsIn the TrichoScan analysis, the total hair count, hair density, percentage of anagen and telogen hair, density, count, and ratio of vellus and terminal hairs in the 0.73 area were calculated. As a result, there were differences in some values between the first analysis and the second analysis. However, these differences were not statistically significant. ConclusionOur study was based on the mucocutaneous side effects of isotretinoin which are telogen effluvium and thinning hair. Our results support that the drug does not alter hair growth parameters in the short term and when very high doses are not used.
Açıklama
Anahtar Kelimeler
acne vulgaris, hair, isotretinoin, telogen effluvium, TrichoScan
Kaynak
JOURNAL OF COSMETIC DERMATOLOGY
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
18
Sayı
2
Künye
İslamoğlu, Z. G. K., Altınyazar, H. C. (2019). Effects of Isotretinoin on the Hair Cycle. Journal of Cosmetic Dermatology, 18(2), 647-651.
