Effects of isotretinoin on the hair cycle

dc.authorid0000-0002-8141-3186
dc.contributor.authorKaya İslamoğlu, Zeynep Gizem.
dc.contributor.authorAltınyazar, Hilmi Cevdet.
dc.date.accessioned2020-03-26T20:13:47Z
dc.date.available2020-03-26T20:13:47Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground/ ObjectivesIsotretinoin is a synthetic vitamin A agent that affects all of the pathogenic factors that suppress sebum production and play a role in the formation of acne. It is frequently used in the treatment of moderate-severe acne vulgaris. However, there are some mucocutaneous and systemic side effects that limit the use of isotretinoin. In this study, we aimed to determine the effect of isotretinoin on hair growth parameters. Material and MethodsIsotretinoin treatment at 0.5mg/kg per day dose was started to patients with moderate-severe acne vulgaris, and hair growth parameters were evaluated before treatment and after 3months of treatment. Parameters were measured by Fotofinder dermatoscopy device using the TrichoScan Professional program. ResultsIn the TrichoScan analysis, the total hair count, hair density, percentage of anagen and telogen hair, density, count, and ratio of vellus and terminal hairs in the 0.73 area were calculated. As a result, there were differences in some values between the first analysis and the second analysis. However, these differences were not statistically significant. ConclusionOur study was based on the mucocutaneous side effects of isotretinoin which are telogen effluvium and thinning hair. Our results support that the drug does not alter hair growth parameters in the short term and when very high doses are not used.en_US
dc.identifier.citationİslamoğlu, Z. G. K., Altınyazar, H. C. (2019). Effects of Isotretinoin on the Hair Cycle. Journal of Cosmetic Dermatology, 18(2), 647-651.
dc.identifier.doi10.1111/jocd.12800en_US
dc.identifier.endpage651en_US
dc.identifier.issn1473-2130en_US
dc.identifier.issn1473-2165en_US
dc.identifier.issue2en_US
dc.identifier.pmid30350907en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage647en_US
dc.identifier.urihttps://dx.doi.org/10.1111/jocd.12800
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37761
dc.identifier.volume18en_US
dc.identifier.wosWOS:000468038000032en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKaya İslamoğlu, Zeynep Gizem.
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofJOURNAL OF COSMETIC DERMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectacne vulgarisen_US
dc.subjecthairen_US
dc.subjectisotretinoinen_US
dc.subjecttelogen effluviumen_US
dc.subjectTrichoScanen_US
dc.titleEffects of isotretinoin on the hair cycleen_US
dc.typeArticleen_US

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